Physicians

Department / Division
Psychiatry / Medical Psychology

Address
DUMC 3503
Durham, NC 27710

Appointment Telephone
919-668-2846

Office Telephone
919-668-1586

Fax Telephone
919-668-0828

Training

• PhD, Clinical/Medical Psychology, Louisiana State University, 2001
• Clinical Internship and Research Fellowship, Westhaven VA/Yale Medical School (Connecticut), 2000-2001

Fellowship

• Geriatric Neuropsychology and Cognitive Neuroscience, Brown Medical School (Rhode Island), 2001-2003

Clinical Interests
Neuropsychological assessment of adults and geriatric patients; evaluation of dementia-related disorders and mild cognitive impairment

Research Interests
Dr. Browndyke is a faculty member of Department of Psychiatry & Behavioral Sciences, and he holds affiliate faculty appointments with the Duke Brain Imaging & Analysis Center (BIAC), Duke Institute for Brain Science (DIBS) and Center for Cognitive Neuroscience (CCN).  He has dual appointment to the Duke University Medical Center and the Durham VA Medical Center, the latter of which is where his clinical work is currently conducted.

Dr. Browndyke's clinical expertise is focused upon; 1.) adult and geriatric populations with an emphasis in the assessment,  diagnosis, and treatment of dementia and related disorders and 2.) forensic/medicolegal evaluation of adults and US veteran patient populations.

Dr. Browndyke's research interests include:

1) The use and development of functional and structural neuroimaging biomarkers for dementia diagnosis, monitoring of disease progression, and treatment outcome.

2) Cognitive performance patterns associated with possible pathological cognitive change in the elderly [e.g., mild cognitive impairment (MCI),cognitive impairment – no dementia (CIND), vascular cognitive impairment - no dementia (V-CIND), etc.].

3) The impact of peri-operative and chronic ischemic cerebrovascular damage on cognitive functioning and dementia risk.

Industry Relationships and Collaborations (What's this?)

This physician has no reported relationships with industry.

Representative Publications
Wee CY, Yap PT, Zhang D, Denny K, Browndyke JN, Potter GG, Welsh-Bohmer KA, Wang L, Shen D. Identification of MCI individuals using structural and functional connectivity networks. Neuroimage. 2012 Feb 1;59(3):2045-56. (2012) Abstract

Hayden KM, Jones RN, Zimmer C, Plassman BL, Browndyke JN, Pieper C, Warren LH, Welsh-Bohmer KA. Factor structure of the National Alzheimer's Coordinating Centers uniform dataset neuropsychological battery: an evaluation of invariance between and within groups over time. Alzheimer Dis Assoc Disord. 2011 Apr-Jun;25(2):128-37. (2011) Abstract

Wee CY, Yap PT, Li W, Denny K, Browndyke JN, Potter GG, Welsh-Bohmer KA, Wang L, Shen D. Enriched white matter connectivity networks for accurate identification of MCI patients. Neuroimage. 2011 Feb 1;54(3):1812-22. (2011) Abstract

Dennis NA, Browndyke JN, Stokes J, Need A, Burke JR, Welsh-Bohmer KA, Cabeza R. Temporal lobe functional activity and connectivity in young adult APOE varepsilon4 carriers. Alzheimers Dement. 2010 Jul;6(4):303-11. (2010) Abstract

Hill BD, Barkemeyer CA, Jones GN, Santa Maria MP, Minor KS, Browndyke JN. Validation of the coin rotation test: a simple, inexpensive, and convenient screening tool for impaired psychomotor processing speed. Neurologist. 2010 Jul;16(4):249-53. (2010) Abstract

Smith PJ, Blumenthal JA, Babyak MA, Craighead L, Welsh-Bohmer KA, Browndyke JN, Strauman TA, Sherwood A. Effects of the dietary approaches to stop hypertension diet, exercise, and caloric restriction on neurocognition in overweight adults with high blood pressure. Hypertension. 2010 Jun;55(6):1331-8. (2010) Abstract

Smith PJ, Blumenthal JA, Hoffman BM, Cooper H, Strauman TA, Welsh-Bohmer K, Browndyke JN, Sherwood A. Aerobic exercise and neurocognitive performance: a meta-analytic review of randomized controlled trials. Psychosom Med. 2010 Apr;72(3):239-52. (2010) Abstract

Linnertz C, Saucier L, Ge D, Cronin KD, Burke JR, Browndyke JN, Hulette CM, Welsh-Bohmer KA, Chiba-Falek O. Genetic regulation of alpha-synuclein mRNA expression in various human brain tissues. PLoS One. 2009;4(10):e7480. (2009) Abstract

Browndyke JN, Paskavitz J, Sweet LH, Cohen RA, Tucker KA, Welsh-Bohmer KA, Burke JR, Schmechel DE. Neuroanatomical correlates of malingered memory impairment: event-related fMRI of deception on a recognition memory task. Brain Inj. 2008 Jun;22(6):481-9. (2008) Abstract

Schmechel DE, Browndyke J, Ghio A. Strategies for dissecting genetic-environmental interactions in neurodegenerative disorders. Neurotoxicology. 2006 Sep;27(5):637-57. (2006)

Gunstad J, Brickman AM, Paul RH, Browndyke J, Moser DJ, Ott BR, Gordon N, Haque O, Cohen RA. Progressive morphometric and cognitive changes in vascular dementia. Arch Clin Neuropsychol. 2005 Mar;20(2):229-41. (2005)

Sweet LH, Paskavitz JF, O'Connor MJ, Browndyke JN, Wellen JW, Cohen RA. FMRI correlates of the WAIS-III symbol search subtest. J Int Neuropsychol Soc. 2005 Jul;11(4):471-6. (2005) Abstract

Browndyke JN, Tucker KA, Woods SP, Beauvals J, Cohen RA, Gottschalk PC, Kosten TR. Examining the effect of cerebral perfusion abnormality magnitude on cognitive performance in recently abstinent chronic cocaine abusers. J Neuroimaging. 2004 Apr;14(2):162-9. (2004) Abstract

Garrett KD, Browndyke JN, Whelihan W, Paul RH, DiCarlo M, Moser DJ, Cohen RA, Ott BR. The neuropsychological profile of vascular cognitive impairment-no dementia: comparisons to patients at risk for cerebrovascular disease and vascular dementia. Arch Clin Neuropsychol. 2004 Sep;19(6):745-57. (2004) Abstract

Gouvier WD, Pinkston JB, Lovejoy JC, Smith SR, Bray GA, Santa Maria MP, Hammer JH, Hilsabeck RC, Smiroldo B, Bentz B, Browndyke J. Neuropsychological and emotional changes during simulated microgravity: effects of triiodothyronine alendronate, and testosterone. Arch Clin Neuropsychol. 2004 Mar;19(2):153-63. (2004)

Tucker KA, Browndyke JN, Gottschalk PC, Cofrancesco AT, Kosten TR. Gender-specific vulnerability for rCBF abnormalities among cocaine abusers. Neuroreport. 2004 Apr 9;15(5):797-801. (2004) Abstract

Tucker KA, Potenza MN, Beauvais JE, Browndyke JN, Gottschalk PC, Kosten TR. Perfusion abnormalities and decision making in cocaine dependence. Biol Psychiatry. 2004 Oct 1;56(7):527-30. (2004) Abstract

Cohen RA, Browndyke JN, Moser DJ, Paul RH, Gordon N, Sweet L. Long-term citicoline (cytidine diphosphate choline) use in patients with vascular dementia: neuroimaging and neuropsychological outcomes. Cerebrovasc Dis. 2003;16(3):199-204. (2003) Abstract

Paul RH, Cohen RA, Moser DJ, Browndyke JN, Davis K, Gordon N, Sweet L, Lawrence JJ, Zawacki T. Sensitivity of the dementia rating scale in vascular dementia: comparison between two sets of criteria to define cognitive impairment. Cerebrovasc Dis. 2003;15(1-2):116-20. (2003) Abstract

Paul RH, Cohen RA, Moser DJ, Ott BR, Sethi M, Sweet L, Browndyke J, Malloy P, Garrett K.  Clinical correlates of cognitive decline in vascular dementia. Cogn Behav Neurol. 2003 Mar;16(1):40-6.  
(2003)

Sweet LH, Paul RH, Cohen RA, Moser D, Ott BR, Gordon N, Browndyke JN, Shah P, Garrett KD. Neuroimaging correlates of dementia rating scale performance at baseline and 12-month follow-up among patients with vascular dementia. J Geriatr Psychiatry Neurol. 2003 Dec;16(4):240-4. (2003) Abstract

Browndyke JN, Albert AL, Malone W, Schatz P, Paul RH, Cohen RA, Tucker KA, Gouvier WD. Computer-related anxiety: examining the impact of technology-specific affect on the performance of a computerized neuropsychological assessment measure. Appl Neuropsychol. 2002;9(4):210-8. (2002) Abstract

Browndyke JN, Moser DJ, Cohen RA, O'Brien DJ, Algina JJ, Haynes WG, Staples ED, Alexander J, Davies LK, Bauer RM. Acute neuropsychological functioning following cardiosurgical interventions associated with the production of intraoperative cerebral microemboli. Clin Neuropsychol. 2002 Dec;16(4):463-71. (2002) Abstract

Schatz P, Browndyke J. Applications of computer-based neuropsychological assessment.  J Head Trauma Rehabil. 2002 Oct;17(5):395-410. (2002)

Paul R, Moser D, Cohen R, Browndyke J, Zawacki T, Gordon N. Dementia severity and pattern of cognitive performance in vascular dementia. Appl Neuropsychol. 2001;8(4):211-7. (2001)