Department / Division
Psychiatry /
Medical Psychology
Address
DUMC 3503
Durham, NC 27710
Appointment Telephone
919-668-3303
Office Telephone
919-668-1586
Fax Telephone
919-668-0828
Clinical Interests
Neuropsychological assessment of adults and geriatric patients; evaluation of age-related cognitive disorders; forensic and medico-legal cognitive, neurobehavioral evaluation
Research Interests
Dr. Browndyke is a faculty member of Department of Psychiatry & Behavioral Sciences, and he holds affiliate faculty appointments with the Duke Brain Imaging & Analysis Center (BIAC), Duke Institute for Brain Science (DIBS) and Center for Cognitive Neuroscience (CCN). He has dual appointment to the Duke University Medical Center and the Durham VA Medical Center, the latter of which is where his clinical work is currently conducted.
Dr. Browndyke's clinical expertise is focused upon; 1.) adult and geriatric populations with an emphasis in the assessment, diagnosis, and treatment of dementia and related disorders and 2.) forensic/medicolegal evaluation of adults and US veteran patient populations.
Dr. Browndyke's research interests include:
1) The use and development of functional and structural neuroimaging biomarkers for dementia diagnosis, monitoring of disease progression, and treatment outcome.
2) Cognitive performance patterns associated with possible pathological cognitive change in the elderly [e.g., mild cognitive impairment (MCI),cognitive impairment – no dementia (CIND), vascular cognitive impairment - no dementia (V-CIND), etc.].
3) The impact of peri-operative and chronic ischemic cerebrovascular damage on cognitive functioning and dementia risk.
This faculty member has no reported relationships with industry.
Representative Publications
Wee, CY; Yap, PT; Zhang, D; Denny, K; Browndyke, JN; Potter, GG; Welsh-Bohmer, KA; Wang, L; Shen, D. Identification of MCI individuals using structural and functional connectivity networks. Neuroimage. 2012;59:2045-2056.
(2012)
Abstract
Hayden, KM; Jones, RN; Zimmer, C; Plassman, BL; Browndyke, JN; Pieper, C; Warren, LH; Welsh-Bohmer, KA. Factor structure of the National Alzheimer's Coordinating Centers uniform dataset neuropsychological battery: an evaluation of invariance between and within groups over time. Alzheimer Disease and Associated Disorders. 2011;25:128-137.
(2011)
Abstract
Wee, CY; Yap, PT; Li, W; Denny, K; Browndyke, JN; Potter, GG; Welsh-Bohmer, KA; Wang, L; Shen, D. Enriched white matter connectivity networks for accurate identification of MCI patients. Neuroimage. 2011;54:1812-1822.
(2011)
Abstract
Dennis, NA; Browndyke, JN; Stokes, J; Need, A; Burke, JR; Welsh-Bohmer, KA; Cabeza, R. Temporal lobe functional activity and connectivity in young adult APOE varepsilon4 carriers. Alzheimer's and Dementia. 2010;6:303-311.
(2010)
Abstract
Hill, BD; Barkemeyer, CA; Jones, GN; Santa Maria, MP; Minor, KS; Browndyke, JN. Validation of the coin rotation test: a simple, inexpensive, and convenient screening tool for impaired psychomotor processing speed. The Neurologist. 2010;16:249-253.
(2010)
Abstract
Smith, PJ; Blumenthal, JA; Babyak, MA; Craighead, L; Welsh-Bohmer, KA; Browndyke, JN; Strauman, TA; Sherwood, A. Effects of the dietary approaches to stop hypertension diet, exercise, and caloric restriction on neurocognition in overweight adults with high blood pressure. Hypertension. 2010;55:1331-1338.
(2010)
Abstract
Smith, PJ; Blumenthal, JA; Hoffman, BM; Cooper, H; Strauman, TA; Welsh-Bohmer, K; Browndyke, JN; Sherwood, A. Aerobic exercise and neurocognitive performance: a meta-analytic review of randomized controlled trials. Psychosomatic Medicine. 2010;72:239-252.
(2010)
Abstract
Linnertz, C; Saucier, L; Ge, D; Cronin, KD; Burke, JR; Browndyke, JN; Hulette, CM; Welsh-Bohmer, KA; Chiba-Falek, O. Genetic regulation of alpha-synuclein mRNA expression in various human brain tissues. PLoS One. 2009;4:e7480.
(2009)
Abstract
Browndyke, JN; Paskavitz, J; Sweet, LH; Cohen, RA; Tucker, KA; Welsh-Bohmer, KA; Burke, JR; Schmechel, DE. Neuroanatomical correlates of malingered memory impairment: event-related fMRI of deception on a recognition memory task. Brain Injury. 2008;22:481-489.
(2008)
Abstract
Sweet, LH; Paskavitz, JF; O'Connor, MJ; Browndyke, JN; Wellen, JW; Cohen, RA. FMRI correlates of the WAIS-III symbol search subtest. Journal of the International Neuropsychological Society. 2005;11:471-476.
(2005)
Abstract
Browndyke, JN; Tucker, KA; Woods, SP; Beauvals, J; Cohen, RA; Gottschalk, PC; Kosten, TR. Examining the effect of cerebral perfusion abnormality magnitude on cognitive performance in recently abstinent chronic cocaine abusers. Journal of Neuroimaging. 2004;14:162-169.
(2004)
Abstract
Garrett, KD; Browndyke, JN; Whelihan, W; Paul, RH; DiCarlo, M; Moser, DJ; Cohen, RA; Ott, BR. The neuropsychological profile of vascular cognitive impairment--no dementia: comparisons to patients at risk for cerebrovascular disease and vascular dementia. Archives of Clinical Neuropsychology. 2004;19:745-757.
(2004)
Abstract
Tucker, KA; Browndyke, JN; Gottschalk, PC; Cofrancesco, AT; Kosten, TR. Gender-specific vulnerability for rCBF abnormalities among cocaine abusers. Neuroreport. 2004;15:797-801.
(2004)
Abstract
Tucker, KA; Potenza, MN; Beauvais, JE; Browndyke, JN; Gottschalk, PC; Kosten, TR. Perfusion abnormalities and decision making in cocaine dependence. Biological Psychiatry. 2004;56:527-530.
(2004)
Abstract
Cohen, RA; Browndyke, JN; Moser, DJ; Paul, RH; Gordon, N; Sweet, L. Long-term citicoline (cytidine diphosphate choline) use in patients with vascular dementia: neuroimaging and neuropsychological outcomes. Cerebrovascular Diseases. 2003;16:199-204.
(2003)
Abstract
Paul, RH; Cohen, RA; Moser, DJ; Browndyke, JN; Davis, K; Gordon, N; Sweet, L; Lawrence, JJ; Zawacki, T. Sensitivity of the dementia rating scale in vascular dementia: comparison between two sets of criteria to define cognitive impairment. Cerebrovascular Diseases. 2003;15:116-120.
(2003)
Abstract
Sweet, LH; Paul, RH; Cohen, RA; Moser, D; Ott, BR; Gordon, N; Browndyke, JN; Shah, P; Garrett, KD. Neuroimaging correlates of dementia rating scale performance at baseline and 12-month follow-up among patients with vascular dementia. Journal of Geriatric Psychiatry and Neurology. 2003;16:240-244.
(2003)
Abstract
Browndyke, JN; Albert, AL; Malone, W; Schatz, P; Paul, RH; Cohen, RA; Tucker, KA; Gouvier, WD. Computer-related anxiety: examining the impact of technology-specific affect on the performance of a computerized neuropsychological assessment measure. 2002;9:210-218.
(2002)
Abstract
Browndyke, JN; Moser, DJ; Cohen, RA; O'Brien, DJ; Algina, JJ; Haynes, WG; Staples, ED; Alexander, J; Davies, LK; Bauer, RM. Acute neuropsychological functioning following cardiosurgical interventions associated with the production of intraoperative cerebral microemboli. The Clinical Neuropsychologist. 2002;16:463-471.
(2002)
Abstract
