Department / Division:
Psychiatry and Behavioral Sciences / Medical Psychology

Address:
DUMC 3503
Durham, NC 27710

Appointment Telephone:
919-668-2846

Office Telephone:
919-668-1586

Fax Telephone:
919-668-0828

• PhD, Clinical/Medical Psychology, Louisiana State University, 2001
• Clinical Internship and Research Fellowship, Westhaven VA/Yale Medical School (Connecticut), 2000-2001
• Post-Doctoral Fellowship, Brown Medical School (Rhode Island), 2001-2003

Clinical Interests:
Neuropsychological assessment of adults and geriatric patients; evaluation of dementia-related disorders and mild cognitive impairment

Research Interests:
Dr. Browndyke is a faculty member of the Joseph and Kathleen Bryan Alzheimer’s Disease Research Center.  In addition to his primary appointment in the Department of Psychiatry & Behavioral Sciences, he holds affiliate faculty appointments with the Duke Brain Imaging & Analysis Center (BIAC) and Center for Cognitive Neuroscience (CCN).  

Dr. Browndyke's clinical expertise is focused upon adult and geriatric populations with an emphasis in the assessment,  diagnosis, and treatment of dementia and related disorders, while his research interests include:

1) The use and development of functional and structural neuroimaging biomarkers for dementia diagnosis, monitoring of disease progression, and treatment outcome.

2) Cognitive performance patterns associated with possible pathological cognitive change in the elderly [e.g., mild cognitive impairment (MCI),cognitive impairment – no dementia (CIND), vascular cognitive impairment - no dementia (V-CIND), etc.].

3) The impact of peri-operative and chronic ischemic cerebrovascular damage on cognitive functioning and dementia risk.

Representative Publications:
Browndyke JN, Paskavitz J, Sweet LH, Cohen RA, Tucker KA, Welsh-Bohmer KA, Burke JR, Schmechel DE. Neuroanatomical correlates of malingered memory impairment: event-related fMRI of deception on a recognition memory task. Brain Inj. 2008 Jun;22(6):481-9. (2008) Abstract

Schmechel DE, Browndyke J, Ghio A. Strategies for dissecting genetic-environmental interactions in neurodegenerative disorders. Neurotoxicology. 2006 Sep;27(5):637-57. (2006)

Sweet LH, Paskavitz JF, O'Connor MJ, Browndyke JN, Wellen JW, Cohen RA. FMRI correlates of the WAIS-III symbol search subtest. J Int Neuropsychol Soc. 2005 Jul;11(4):471-6. (2005) Abstract

Gunstad J, Brickman AM, Paul RH, Browndyke J, Moser DJ, Ott BR, Gordon N, Haque O, Cohen RA. Progressive morphometric and cognitive changes in vascular dementia. Arch Clin Neuropsychol. 2005 Mar;20(2):229-41. (2005)

Tucker KA, Potenza MN, Beauvais JE, Browndyke JN, Gottschalk PC, Kosten TR. Perfusion abnormalities and decision making in cocaine dependence. Biol Psychiatry. 2004 Oct 1;56(7):527-30. (2004) Abstract

Tucker KA, Browndyke JN, Gottschalk PC, Cofrancesco AT, Kosten TR. Gender-specific vulnerability for rCBF abnormalities among cocaine abusers. Neuroreport. 2004 Apr 9;15(5):797-801. (2004) Abstract

Gouvier WD, Pinkston JB, Lovejoy JC, Smith SR, Bray GA, Santa Maria MP, Hammer JH, Hilsabeck RC, Smiroldo B, Bentz B, Browndyke J. Neuropsychological and emotional changes during simulated microgravity: effects of triiodothyronine alendronate, and testosterone. Arch Clin Neuropsychol. 2004 Mar;19(2):153-63. (2004)

Garrett KD, Browndyke JN, Whelihan W, Paul RH, DiCarlo M, Moser DJ, Cohen RA, Ott BR. The neuropsychological profile of vascular cognitive impairment-no dementia: comparisons to patients at risk for cerebrovascular disease and vascular dementia. Arch Clin Neuropsychol. 2004 Sep;19(6):745-57. (2004) Abstract

Browndyke JN, Tucker KA, Woods SP, Beauvals J, Cohen RA, Gottschalk PC, Kosten TR. Examining the effect of cerebral perfusion abnormality magnitude on cognitive performance in recently abstinent chronic cocaine abusers. J Neuroimaging. 2004 Apr;14(2):162-9. (2004) Abstract

Sweet LH, Paul RH, Cohen RA, Moser D, Ott BR, Gordon N, Browndyke JN, Shah P, Garrett KD. Neuroimaging correlates of dementia rating scale performance at baseline and 12-month follow-up among patients with vascular dementia. J Geriatr Psychiatry Neurol. 2003 Dec;16(4):240-4. (2003) Abstract

Paul RH, Cohen RA, Moser DJ, Ott BR, Sethi M, Sweet L, Browndyke J, Malloy P, Garrett K.  Clinical correlates of cognitive decline in vascular dementia. Cogn Behav Neurol. 2003 Mar;16(1):40-6.  
(2003)

Paul RH, Cohen RA, Moser DJ, Browndyke JN, Davis K, Gordon N, Sweet L, Lawrence JJ, Zawacki T. Sensitivity of the dementia rating scale in vascular dementia: comparison between two sets of criteria to define cognitive impairment. Cerebrovasc Dis. 2003;15(1-2):116-20. (2003) Abstract

Cohen RA, Browndyke JN, Moser DJ, Paul RH, Gordon N, Sweet L. Long-term citicoline (cytidine diphosphate choline) use in patients with vascular dementia: neuroimaging and neuropsychological outcomes. Cerebrovasc Dis. 2003;16(3):199-204. (2003) Abstract

Schatz P, Browndyke J. Applications of computer-based neuropsychological assessment.  J Head Trauma Rehabil. 2002 Oct;17(5):395-410. (2002)

Browndyke JN, Moser DJ, Cohen RA, O'Brien DJ, Algina JJ, Haynes WG, Staples ED, Alexander J, Davies LK, Bauer RM. Acute neuropsychological functioning following cardiosurgical interventions associated with the production of intraoperative cerebral microemboli. Clin Neuropsychol. 2002 Dec;16(4):463-71. (2002) Abstract

Browndyke JN, Albert AL, Malone W, Schatz P, Paul RH, Cohen RA, Tucker KA, Gouvier WD. Computer-related anxiety: examining the impact of technology-specific affect on the performance of a computerized neuropsychological assessment measure. Appl Neuropsychol. 2002;9(4):210-8. (2002) Abstract

Paul R, Moser D, Cohen R, Browndyke J, Zawacki T, Gordon N. Dementia severity and pattern of cognitive performance in vascular dementia. Appl Neuropsychol. 2001;8(4):211-7. (2001)