Department / Division:
Surgery / General Surgery

Address:
DUMC 2622
Durham, NC 27710

Appointment Telephone:
919-681-2884

Office Telephone:
919-681-2533

Fax Telephone:
919-681-1094

• MD, University of Vermont College of Medicine, 1991

• General and Thoracic Surgery, Duke University Medical Center, 1992-1999

• Vascular Surgery, Duke University Medical Center, 2001-2002

• PhD, Cell and Molecular Biology, University of Vermont, 1992

Clinical Interests:
Vascular surgery, hemodialysis access, peripheral arterial disease, aortic disease, carotid artery disease, endovascular surgery, surgical disorders of vascular thrombosis and blood coagulation

Research Interests:
The research interests of my laboratory include the study of vascular biology and cellular differentiation of vascular tissue, the proteolytic and cell mediated regulation of blood coagulation, inflammatory mediated thrombosis, and the development of bioengineered blood vessels.  The clinical interests of my laboratory include the study of novel therapies for vascular and cardiovascular surgery, thrombosis related to surgical procedures, clinical inhibitors of blood coagulation proteases, and the study of the immune response to biologics used in surgery.

Representative Publications:
Su Z, Izumi T, Thames EH, Lawson JH, Ortel TL. Antiphospholipid antibodies after surgical exposure to topical bovine thrombin. J Lab Clin Med. 2002 Jun;139(6):349-56. (2002) Abstract

Gaca JG, Lesher A, Aksoy O, Gonzalez-Stawinski GV, Platt JL, Lawson JH, Parker W, Davis RD. Disseminated intravascular coagulation in association with pig-to-primate pulmonary xenotransplantation. Transplantation. 2002 Jun 15;73(11):1717-23. (2002) Abstract

White, R., Rusconi, C., Scardino, E., Wolberg, A., Lawson, J., Hoffman, M., and Sullenger, B., Generation of Species Cross-Reactive Aptamers Using "toggel" SELEX, Molecular Therapies, (In Press) 2001. (2001)

Schoenecker, J., Fields, R., Cancel, Q., Day, J., Lawson, J., Coagulation Abnormalities, Unbound Surgery, Pappas, T. and Purcel, G eds. (In Press), 2001 (2001)

Schoenecker JG, Johnson RK, Lesher AP, Day JD, Love SD, Hoffman MR, Ortel TL, Parker W, Lawson JH. Exposure of mice to topical bovine thrombin induces systemic autoimmunity. Am J Pathol. 2001 Nov;159(5):1957-69. (2001) Abstract

Ortel TL, Mercer MC, Thames EH, Moore KD, Lawson JH. Immunologic impact and clinical outcomes after surgical exposure to bovine thrombin. Ann Surg. 2001 Jan;233(1):88-96. (2001) Abstract

Lawson, J.H., Anderson, R.W., The Research Program as a Business Enterprise, Surgical Research, Souba, W.W. and Wilmore, D.W. eds., Academic Press, pp 1279-1286, 2001 (2001)

Gaca JG, Lesher BA, Lawson JH, Parker W, Davis RD., Coagulopathy Induced by Pulmonary Xenotransplantation, Transplantation, (In Press) 2001 (2001)

Diamond, L.E., Quinn, C.M., Martin, M.J., Lawson, J.H., Platt, J.L., Logan, J.S. A Human CD46 Transgenic Pig Model System for the Study of Discordant Xenotransplantation. Transplantation, 71(1):132-142, 2001. (2001)