Durham, NC 27710
Vascular surgery, hemodialysis access, peripheral arterial disease, aortic disease, carotid artery disease, endovascular surgery, surgical disorders of vascular thrombosis and blood coagulation
The research interests of my laboratory include the study of vascular biology and cellular differentiation of vascular tissue, the proteolytic and cell mediated regulation of blood coagulation, inflammatory mediated thrombosis, and the development of bioengineered blood vessels. The clinical interests of my laboratory include the study of novel therapies for vascular and cardiovascular surgery, thrombosis related to surgical procedures, clinical inhibitors of blood coagulation proteases, and the study of the immune response to biologics used in surgery.
This faculty member (or a member of their immediate family) has a working relationship (i.e. consulting, research, and/or educational services) with the companies listed below. These relations have been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts.
Gaca, JG; Lesher, A; Aksoy, O; Gonzalez-Stawinski, GV; Platt, JL; Lawson, JH; Parker, W; Davis, RD. Disseminated intravascular coagulation in association with pig-to-primate pulmonary xenotransplantation. Transplantation. 2002;73:1717-1723. (2002) Abstract
Su, Z; Izumi, T; Thames, EH; Lawson, JH; Ortel, TL. Antiphospholipid antibodies after surgical exposure to topical bovine thrombin. Translational Research: the journal of laboratory and clinical medicine. 2002;139:349-356. (2002) Abstract
Ortel, TL; Mercer, MC; Thames, EH; Moore, KD; Lawson, JH. Immunologic impact and clinical outcomes after surgical exposure to bovine thrombin. Annals of Surgery. 2001;233:88-96. (2001) Abstract
Schoenecker, JG; Johnson, RK; Lesher, AP; Day, JD; Love, SD; Hoffman, MR; Ortel, TL; Parker, W; Lawson, JH. Exposure of mice to topical bovine thrombin induces systemic autoimmunity. American Journal of Pathology. 2001;159:1957-1969. (2001) Abstract