Physicians

Department / Division
Radiation Oncology / Radiation Onc-Clinical Sup

Address
DUMC 3085
Durham, NC 27710

Appointment Telephone
919-660-2100

Office Telephone
919-668-5213

Fax Telephone
919-668-7345

Training

• MD, Wake Forest University School of Medicine (North Carolina), 2001

Residency

• Internal Medicine, Moses Cone Memorial Hospital (North Carolina), 2001-2002
• Radiation Oncology, UNC Hospitals, 2002-2006

Clinical Interests
Radiotherapy for women with breast cancer

Research Interests
My primary clinical and research focus revolves around women with breast cancer. Specifically, I am interested in studying breast cancer subtype specific (luminal, basal) radiation response in human breast tumors and utilizing that information to design biologically based radiotherapy trials.

Industry Relationships and Collaborations (What's this?)

This faculty member (or a member of their immediate family) has a working relationship (i.e. consulting, research, and/or educational services) with the companies listed below. These relations have been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts.

• National Institutes of Health
• New Life After Cancer
• Susan G. Komen for the Cure
• Varian Medical Systems

Representative Publications
Betof, AS; Rabbani, ZN; Hardee, ME; Kim, SJ; Broadwater, G; Bentley, RC; Snyder, SA; Vujaskovic, Z; Oosterwijk, E; Harris, LN; Horton, JK; Dewhirst, MW; Blackwell, KL. Carbonic anhydrase IX is a predictive marker of doxorubicin resistance in early-stage breast cancer independent of HER2 and TOP2A amplification. British Journal of Cancer. 2012;106:916-922. (2012) Abstract

Cuneo, KC; Dash, RC; Wilke, LG; Horton, JK; Koontz, BF. Risk of invasive breast cancer and ductal carcinoma in situ in women with atypical papillary lesions of the breast. The Breast Journal. 2012;18:475-478. (2012) Abstract

Kimple, RJ; Horton, JK; Livasy, CA; Shields, JM; Lawrence, JA; Chiu, WM; Ivanova, A; Ollila, DW; Carey, LA; Halle, JS; Sartor, CI; Dees, EC. Phase I study and biomarker analysis of lapatinib and concurrent radiation for locally advanced breast cancer. The Oncologist. 2012;17:1496-1503. (2012) Abstract

Palta, M; Yoo, S; Adamson, JD; Prosnitz, LR; Horton, JK. Preoperative single fraction partial breast radiotherapy for early-stage breast cancer. International Journal of Radiation: Oncology - Biology - Physics. 2012;82:37-42. (2012) Abstract

Yoo, S; Wu, Q; O'Daniel, J; Horton, J; Yin, FF. Comparison of 3D conformal breast radiation treatment plans using the anisotropic analytical algorithm and pencil beam convolution algorithm. Radiotherapy and Oncology. 2012;103:172-177. (2012) Abstract

Shah, MM; Horton, JK; Yoo, S; Hubbs, JL; Demirci, S; Light, KL; Temple, K; Patrone, M; Marks, LB. A comparison of clinical and dosimetric outcomes in patients receiving partial breast irradiation with photon-only versus mixed photon/electron treatment plans. Medical Dosimetry. 2011;36:423-428. (2011) Abstract

Horton, JK; Halle, J; Ferraro, M; Carey, L; Moore, DT; Ollila, D; Sartor, CI. Radiosensitization of chemotherapy-refractory, locally advanced or locally recurrent breast cancer with trastuzumab: a phase II trial. International Journal of Radiation: Oncology - Biology - Physics. 2010;76:998-1004. (2010) Abstract

Qiu, JJ; Chang, Z; Wu, QJ; Yoo, S; Horton, J; Yin, FF. Impact of volumetric modulated arc therapy technique on treatment with partial breast irradiation. International Journal of Radiation: Oncology - Biology - Physics. 2010;78:288-296. (2010) Abstract

Godat, LN; Horton, JK; Shen, P; Stewart, JH; Wentworth, S; Levine, EA. Recurrence after mastectomy for ductal carcinoma in situ. American Surgeon. 2009;75:592-595. (2009) Abstract

Lally, BE; Geiger, AM; Urbanic, JJ; Butler, JM; Wentworth, S; Perry, MC; Wilson, LD; Horton, JK; Detterbeck, FC; Miller, AA; Thomas, CR; Blackstock, AW. Trends in the outcomes for patients with limited stage small cell lung cancer: An analysis of the Surveillance, Epidemiology, and End Results database. Lung Cancer. 2009;64:226-231. (2009) Abstract

Prosnitz, LR; Horton, J; Wallner, PE. Accelerated partial breast irradiation: caution and concern from an ASTRO task force. International Journal of Radiation: Oncology - Biology - Physics. 2009;74:981-984. (2009) Abstract

Horton, JK; Halle, JS; Chang, SX; Sartor, CI. Comparison of three concomitant boost techniques for early-stage breast cancer. International Journal of Radiation: Oncology - Biology - Physics. 2006;64:168-175. (2006) Abstract

Horton, JK; Tepper, JE. Staging of colorectal cancer: past, present, and future. Clinical Colorectal Cancer. 2005;4:302-312. (2005) Abstract

Horton, JK. Hospice. Care when there is no cure. North Carolina Medical Journal. 2001;62:86-90. (2001) Abstract