Department / Division:
Medicine / Medical Oncology

Address:
DUMC 3052
Durham, NC 27710

Appointment Telephone:
919-668-6688

Office Telephone:
919-681-5257

Fax Telephone:
919-613-5228

• MD, Jefferson Medical College of Thomas Jefferson University (Pennsylvania), 1988

• Internal Medicine, Michael Reese Hospital (Illinois), 1988-1991
• Oncology, Johns Hopkins Oncology Center (Maryland), 1992-1996

Clinical Interests:
Phase 1 clinical trials involving new anti-cancer drugs, drug combinations, and combinations of new drugs with radiation; cancers of the GI system

Research Interests:
Particular Clinical Interests and Skills: Phase I clinical trials involving new anti cancer drugs; drug combinations; and combinations of new drugs with radiation; cancers of the GI system

Representative Publications:
Ochoa L, Hurwitz HI, Wilding G, Cohen D, Thomas JP, Schwartz G, Monroe P, Petros WP, Ertel VP, Hsieh A, Hoffman C, Drengler R, Magnum S, Rowinsky EK. Pharmacokinetics and bioequivalence of a combined oral formulation of eniluracil, an inactivator of dihydropyrimidine dehydrogenase, and 5-fluorouracil in patients with advanced solid malignancies. Ann Oncol. 2000 Oct;11(10):1313-22. (2000)

Chakravarthy A, Abrams RA, Yeo CJ, Korman LT, Donehower RC, Hruban RH, Zahurek ML, Grochow LB, O'Reilly S, Hurwitz H, Jaffee EM, Lillemoe KD, Cameron JL. Intensified adjuvant combined modality therapy for resected periampullary adenocarcinoma: acceptable toxicity and suggestion of improved 1-year disease-free survival. Int J Radiat Oncol Biol Phys. 2000 Nov 1;48(4):1089-96. (2000)

White R, Lee C, Anscher M, Gottfried M, Wolff R, Keogan M, Pappas T, Hurwitz H, Tyler D. Preoperative chemoradiation for patients with locally advanced adenocarcinoma of the pancreas. Ann Surg Oncol. 1999 Jan-Feb;6(1):38-45. (1999)

Katz A. Vlodavsky I. Davies M. Miao HQ. Ben-Sasson SA. Darmon D. Hurwitz H. Borgel H. Benezra M. Antiproliferative activity to glomerular mesangial cells and receptor binding of a heparin-mimicking polyaromatic anionic compound. [Journal Article] Journal of the American Society of Nephrology. 8(11):1688-97, 1997 Nov. (1997)

Abrams RA. Cardinale RM. Enger C. Haulk TL. Hurwitz H. Osterman F. Sitzmann JV. Influence of prognostic groupings and treatment results in the management of unresectable hepatoma: experience with Cisplatinum-based chemoradiotherapy in 76 patients. [Journal Article] International Journal of Radiation Oncology, Biology, Physics. 39(5):1077-85, 1997 Dec (1997)