G. Michael Felker, MD, MHS
Department / Division
Medicine /
Medicine - Cardiology
Address
DUMC 3850
Durham, NC 27710
Appointment Telephone
919-668-8270
Office Telephone
919-668-8919
Fax Telephone
919-668-7063
- MD, Duke University School of Medicine, 1993
- Medicine, Johns Hopkins Hospital (Maryland), 1993-1998
- Cardiology, Johns Hopkins Hospital (Maryland), 1998-1999
- Cardiology, Duke University Medical Center, 1999-2002
- Cardiac Transplantation, Duke University Medical Center, 2002
- Fellow, American College of Cardiology
- Fellow, American Heart Association
Clinical Interests
Heart failure, cardiac transplantation, novel therapies for advanced heart
failure
This faculty member (or a member of their immediate family) has a working relationship (i.e. consulting, research, and/or educational services) with the companies listed below. These relations have been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts.
- Amgen, Inc.
- BG Medicine
- Celladon
- Critical Diagnostics
- Geron Corporation
- Medpace, Inc.
- Medtronic Inc.
- Novartis
- Otsuka
- Roche Diagnostics
- St Judes
- Trevena Inc.
- Zensun
Representative Publications
Teerlink, JR; Cotter, G; Davison, BA; Felker, GM; Filippatos, G; Greenberg, BH; Ponikowski, P; Unemori, E; Voors, AA; Adams, KF; Dorobantu, MI; Grinfeld, LR; Jondeau, G; Marmor, A; Masip, J; Pang, PS; Werdan, K; Teichman, SL; Trapani, A; Bush, CA; Saini, R; Schumacher, C; Severin, TM; Metra, M; RELAXin in Acute Heart Failure (RELAX-AHF) Investigators. Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial. Lancet. 2013;381:29-39.
(2013)
Abstract
Allen, LA; Stevenson, LW; Grady, KL; Goldstein, NE; Matlock, DD; Arnold, RM; Cook, NR; Felker, GM; Francis, GS; Hauptman, PJ; Havranek, EP; Krumholz, HM; Mancini, D; Riegel, B; Spertus, JA; American Heart Association, ; Council on Quality of Care and Outcomes Research, ; Council on Cardiovascular Nursing, ; Council on Clinical Cardiology, ; Council on Cardiovascular Radiology and Intervention, ; Council on Cardiovascular Surgery and Anesthesia. Decision making in advanced heart failure: a scientific statement from the American Heart Association. Circulation. 2012;125:1928-1952.
(2012)
Abstract
Bart, BA; Goldsmith, SR; Lee, KL; Givertz, MM; O'Connor, CM; Bull, DA; Redfield, MM; Deswal, A; Rouleau, JL; LeWinter, MM; Ofili, EO; Stevenson, LW; Semigran, MJ; Felker, GM; Chen, HH; Hernandez, AF; Anstrom, KJ; McNulty, SE; Velazquez, EJ; Ibarra, JC; Mascette, AM; Braunwald, E; Heart Failure Clinical Research Network. Ultrafiltration in decompensated heart failure with cardiorenal syndrome. New England Journal of Medicine. 2012;367:2296-2304.
(2012)
Abstract
Felker, GM; Fiuzat, M; Shaw, LK; Clare, R; Whellan, DJ; Bettari, L; Shirolkar, SC; Donahue, M; Kitzman, DW; Zannad, F; Piña, IL; O'Connor, CM. Galectin-3 in ambulatory patients with heart failure: results from the HF-ACTION study. Circulation. Heart failure. 2012;5:72-78.
(2012)
Abstract
Felker, GM; Hasselblad, V; Tang, WH; Hernandez, AF; Armstrong, PW; Fonarow, GC; Voors, AA; Metra, M; McMurray, JJ; Butler, J; Heizer, GM; Dickstein, K; Massie, BM; Atar, D; Troughton, RW; Anker, SD; Califf, RM; Starling, RC; O'Connor, CM. Troponin I in acute decompensated heart failure: insights from the ASCEND-HF study. European Journal of Heart Failure. 2012;14:1257-1264.
(2012)
Abstract
Felker, GM; Lee, KL; Bull, DA; Redfield, MM; Stevenson, LW; Goldsmith, SR; LeWinter, MM; Deswal, A; Rouleau, JL; Ofili, EO; Anstrom, KJ; Hernandez, AF; McNulty, SE; Velazquez, EJ; Kfoury, AG; Chen, HH; Givertz, MM; Semigran, MJ; Bart, BA; Mascette, AM; Braunwald, E; O'Connor, CM; NHLBI Heart Failure Clinical Research Network. Diuretic strategies in patients with acute decompensated heart failure. New England Journal of Medicine. 2011;364:797-805.
(2011)
Abstract
Felker, GM. Coenzyme Q10 and statins in heart failure: the dog that didn't bark. Journal of the American College of Cardiology. 2010;56:1205-1206.
(2010)
Abstract
Felker, GM. Too much, too little, or just right?: untangling endogenous erythropoietin in heart failure. Circulation. 2010;121:191-193.
(2010)
Abstract
Felker, GM; Maisel, AS. A global rank end point for clinical trials in acute heart failure. Circulation. Heart failure. 2010;3:643-646.
(2010)
Abstract
Felker, GM; Pang, PS; Adams, KF; Cleland, JG; Cotter, G; Dickstein, K; Filippatos, GS; Fonarow, GC; Greenberg, BH; Hernandez, AF; Khan, S; Komajda, M; Konstam, MA; Liu, PP; Maggioni, AP; Massie, BM; McMurray, JJ; Mehra, M; Metra, M; O'Connell, J; O'Connor, CM; Pina, IL; Ponikowski, P; Sabbah, HN; Teerlink, JR; Udelson, JE; Yancy, CW; Zannad, F; Gheorghiade, M; International AHFS Working Group. Clinical trials of pharmacological therapies in acute heart failure syndromes: lessons learned and directions forward. Circulation. Heart failure. 2010;3:314-325.
(2010)
Abstract
Kociol, RD; Pang, PS; Gheorghiade, M; Fonarow, GC; O'Connor, CM; Felker, GM. Troponin elevation in heart failure prevalence, mechanisms, and clinical implications. Journal of the American College of Cardiology. 2010;56:1071-1078.
(2010)
Abstract
Metra, M; Teerlink, JR; Felker, GM; Greenberg, BH; Filippatos, G; Ponikowski, P; Teichman, SL; Unemori, E; Voors, AA; Weatherley, BD; Cotter, G. Dyspnoea and worsening heart failure in patients with acute heart failure: results from the Pre-RELAX-AHF study. European Journal of Heart Failure. 2010;12:1130-1139.
(2010)
Abstract
Szczech, LA; Barnhart, HX; Sapp, S; Felker, GM; Hernandez, A; Reddan, D; Califf, RM; Inrig, JK; Patel, UD; Singh, AK. A secondary analysis of the CHOIR trial shows that comorbid conditions differentially affect outcomes during anemia treatment. Kidney International. 2010;77:239-246.
(2010)
Abstract
van Kimmenade, RR; Mohammed, AA; Uthamalingam, S; van der Meer, P; Felker, GM; Januzzi, JL. Red blood cell distribution width and 1-year mortality in acute heart failure. European Journal of Heart Failure. 2010;12:129-136.
(2010)
Abstract
Adams, KF; Patterson, JH; Oren, RM; Mehra, MR; O'Connor, CM; Piña, IL; Miller, AB; Chiong, JR; Dunlap, SH; Cotts, WG; Felker, GM; Schocken, DD; Schwartz, TA; Ghali, JK; STAMINA-HFP Registry Investigators. Prospective assessment of the occurrence of anemia in patients with heart failure: results from the Study of Anemia in a Heart Failure Population (STAMINA-HFP) Registry. American Heart Journal. 2009;157:926-932.
(2009)
Abstract
Adams, KF; Piña, IL; Ghali, JK; Wagoner, LE; Dunlap, SH; Schwartz, TA; Stough, WG; Mehra, MR; Felker, GM; Chiong, JR; Patterson, JH; Kim, J; Butler, J; Oren, RM. Prospective evaluation of the association between hemoglobin concentration and quality of life in patients with heart failure. American Heart Journal. 2009;158:965-971.
(2009)
Abstract
Allen, LA; Anstrom, KJ; Horton, JR; Shaw, LK; Eisenstein, EL; Felker, GM. Relationship between anemia and health care costs in heart failure. Journal of Cardiac Failure. 2009;15:843-849.
(2009)
Abstract
Allen, LA; Felker, GM; Pocock, S; McMurray, JJ; Pfeffer, MA; Swedberg, K; Wang, D; Yusuf, S; Michelson, EL; Granger, CB; CHARM Investigators. Liver function abnormalities and outcome in patients with chronic heart failure: data from the Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity (CHARM) program. European Journal of Heart Failure. 2009;11:170-177.
(2009)
Abstract
Allen, LA; Hernandez, AF; O'Connor, CM; Felker, GM. End points for clinical trials in acute heart failure syndromes. Journal of the American College of Cardiology. 2009;53:2248-2258.
(2009)
Abstract
Felker, GM; Hasselblad, V; Hernandez, AF; O'Connor, CM. Biomarker-guided therapy in chronic heart failure: a meta-analysis of randomized controlled trials. American Heart Journal. 2009;158:422-430.
(2009)
Abstract
Felker, GM; O'Connor, CM; Braunwald, E; Heart Failure Clinical Research Network Investigators. Loop diuretics in acute decompensated heart failure: necessary? Evil? A necessary evil?. Circulation. Heart failure. 2009;2:56-62.
(2009)
Abstract
Felker, GM; Whellan, D; Kraus, WE; Clare, R; Zannad, F; Donahue, M; Adams, K; McKelvie, R; Piña, IL; O'Connor, CM; HF-ACTION Investigators. N-terminal pro-brain natriuretic peptide and exercise capacity in chronic heart failure: data from the Heart Failure and a Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) study. American Heart Journal. 2009;158:S37-S44.
(2009)
Abstract
Pal, JD; Piacentino, V; Cuevas, AD; Depp, T; Daneshmand, MA; Hernandez, AF; Felker, GM; Lodge, AJ; Rogers, JG; Milano, CA. Impact of left ventricular assist device bridging on posttransplant outcomes. Annals of Thoracic Surgery. 2009;88:1457-1461.
(2009)
Abstract
Teerlink, JR; Metra, M; Felker, GM; Ponikowski, P; Voors, AA; Weatherley, BD; Marmor, A; Katz, A; Grzybowski, J; Unemori, E; Teichman, SL; Cotter, G. Relaxin for the treatment of patients with acute heart failure (Pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study. Lancet. 2009;373:1429-1439.
(2009)
Abstract
Allen, LA; Yager, JE; Funk, MJ; Levy, WC; Tulsky, JA; Bowers, MT; Dodson, GC; O'Connor, CM; Felker, GM. Discordance between patient-predicted and model-predicted life expectancy among ambulatory patients with heart failure. JAMA: Journal of the American Medical Association. 2008;299:2533-2542.
(2008)
Abstract
