Physicians

Department / Division
Surgery / Cardiovascular & Thoracic

Address
DUMC 3851
Durham, NC 27710

Appointment Telephone
919-681-5789

Office Telephone
919-681-5789

Fax Telephone
919-681-8912

Training

• MD, Johns Hopkins University School of Medicine (Maryland), 1980

Residency

• Surgery, Duke University Medical Center, 1980-1987

Fellowship

• Thoracic Surgery, Duke University Medical Center, 1987-1989

Clinical Interests
Minimally invasive valve and coronary surgery; valve repair and replacement; robotic heart surgery; septal myectomy for hypertrophic obstructive cardiomyopathy; minimally invasive maze procedure for atrial fibrillation

Research Interests
Current clinical research projects examine the effects of patient characteristics and surgical technique in outcome after minimally invasive cardiac surgery, valve repair and replacement, and coronary artery bypass grafting.
Prior work has examined the role of surgical therapy versus medical therapy in aortic dissection, load-independent means to quantify left and right ventricular function, and management of complex coronary disease.

Industry Relationships and Collaborations (What's this?)

This physician has no reported relationships with industry.

Representative Publications
Glower D, Lee T, Desai B. Aortic Valve Replacement via Right Mini-Thoracotomy in 306 Consecutive Patients.  Innovations 5; 326-30, 2010 (2010)

Lee T, Glower D, Desai B, Milano C, Jaggers J.  Comparison of mini-thoracotomy versus sternotomy in 304 consecutive tricuspid valve operations. Innovations 5:3-6,2010. (2010)

Daneshmand MA, Milano CA, Rankin JS, Honeycutt EF, Swaminathan M, Shaw LK, Smith PK, Glower DD. Mitral valve repair for degenerative disease: a 20-year experience. Ann Thorac Surg. 2009 Dec;88(6):1828-37. (2009) Abstract

Feldman T, Kar S, Rinaldi M, Fail P, Hermiller J, Smalling R, Whitlow PL, Gray W, Low R, Herrmann HC, Lim S, Foster E, Glower D. Percutaneous Mitral Repair with the MitraClip® Device: Safety and Midterm Durability in the Initial EVEREST Cohort. J Am Coll Cardiol 2009; 54(8):686-94 (2009)

Glower D, Desai B.  Early Results of Edge-to-Edge Alfieri Mitral Repair via Right Mini-Thoracotomy in 68 Consecutive Patients. Innovations 4; 256-60, 2009. (2009)

Glower DD, Bashore TM, Harrison JK, Wang A, Gehrig T, Rankin JS. Pure annular dilation as a cause of mitral regurgitation: a clinically distinct entity of female heart disease. J Heart Valve Dis. 2009 May;18(3):284-8. (2009) Abstract

Lee TC, Desai B, Glower DD. Results of 141 consecutive minimally invasive tricuspid valve operations: an 11-year experience. Ann Thorac Surg. 2009 Dec;88(6):1845-50. (2009) Abstract

Feldman T, Glower D.  Patient selection for percutaneous mitral valve repair: insight from early clinical trial applications.  Nat Clin Pract Cardiovasc Med.  5:84-90, 2008 (2008)

Milano CA, Daneshmand MA, Rankin JS, Honeycutt E, Williams ML, Swaminathan M, Linblad L, Shaw LK, Glower DD, Smith PK. Survival prognosis and surgical management of ischemic mitral regurgitation. Ann Thorac Surg. 2008 Sep;86(3):735-44. (2008) Abstract

Martin JS, Davis RD, Glower DD.  Intermediate-term results of 505 consecutive mini-thoracotomy mitral valve procedures.  Innovations 1:99-104, 2006 (2006)

Nienaber JJ, Glower DD. Minitransseptal versus left atrial approach to the mitral valve: a comparison of outcomes. Ann Thorac Surg. 2006 Sep;82(3):834-9; discussion 839. (2006) Abstract

Rankin JS, Hammill BG, Ferguson TB Jr, Glower DD, O'Brien SM, DeLong ER, Peterson ED, Edwards FH. Determinants of operative mortality in valvular heart surgery. J Thorac Cardiovasc Surg. 2006 Mar;131(3):547-57. (2006) Abstract

Glower DD, Tuttle RH, Shaw LK, Orozco RE, Rankin JS. Patient survival characteristics after routine mitral valve repair for ischemic mitral regurgitation. J Thorac Cardiovasc Surg. 2005 Apr;129(4):860-8. (2005) Abstract

Glower DD. Management of Chronic Aortic Regurgitation. Curr Treat Options Cardiovasc Med. 2003 Dec;5(6):511-520. (2003) Abstract

McCreath BJ, Swaminathan M, Booth JV, Phillips-Bute B, Chew ST, Glower DD, Stafford-Smith M. Mitral valve surgery and acute renal injury: port access versus median sternotomy. Ann Thorac Surg. 2003 Mar;75(3):812-9. (2003) Abstract

Shah AS and Glower DD. Port access mitral valve surgery.  In Minimally Invasive Cardiac Surgery. Oz MC and Goldstein DJ, eds.  Totowa, NJ. Humana Press, Inc., 2003. (2003)

Trichon BH, Glower DD, Shaw LK, Cabell CH, Anstrom KJ, Felker GM, O'Connor CM. Survival after coronary revascularization, with and without mitral valve surgery, in patients with ischemic mitral regurgitation. Circulation. 2003 Sep 9;108 Suppl 1:II103-10. (2003) Abstract

Burfeind WR, Glower DD, Davis RD, Landolfo KP, Lowe JE, Wolfe WG. Mitral surgery after prior cardiac operation: port-access versus sternotomy or thoracotomy. Ann Thorac Surg. 2002 Oct;74(4):S1323-5. (2002) Abstract

Glower D, Landolfo K, Kypson A, Bashore T, Harrison K, Wang A. Is port access applicable to complex mitral valve repair? Heart Surgery Forum 5:Suppl 1,2002, www.hsforum.com. (2002)

Kypson AP, Glower DD. Minimally invasive tricuspid operation using port access. Ann Thorac Surg. 2002 Jul;74(1):43-5. (2002) Abstract

Kypson AP, Glower DD. Port-access approach for combined aortic and mitral valve surgery. Ann Thorac Surg. 2002 May;73(5):1657-8. (2002) Abstract

Tripp HF, Glower DD, Lowe JE, Wolfe WG. Comparison of port access to sternotomy in tricuspid or mitral/tricuspid operations. Heart Surg Forum. 2002;5(2):136-40. (2002) Abstract

Cen YY, Glower DD, Landolfo K, Lowe JE, Davis RD, Wolfe WG, Pieper C, Peterson B. Comparison of survival after mitral valve replacement with biologic and mechanical valves in 1139 patients. J Thorac Cardiovasc Surg. 2001 Sep;122(3):569-77. (2001) Abstract

Glower DD, Siegel LC, Galloway AC, Ribakove G, Grossi E, Robinson N, Ryan WH, Colvin S, Shemin R. Predictors of operative time in multicenter port-access valve registry: institutional differences in learning. Heart Surg Forum. 2001;4(1):40-6. (2001) Abstract

Glower DD, Siegel LC, Frischmeyer KJ, Galloway AC, Ribakove GH, Grossi EA, Robinson NB, Ryan WH, Colvin SB. Predictors of outcome in a multicenter port-access valve registry. Ann Thorac Surg. 2000 Sep;70(3):1054-9. (2000) Abstract

Galloway AC, Shemin RJ, Glower DD, Boyer JH Jr, Groh MA, Kuntz RE, Burdon TA, Ribakove GH, Reitz BA, Colvin SB. First report of the Port Access International Registry. Ann Thorac Surg. 1999 Jan;67(1):51-6; discussion 57-8. (1999) Abstract

Glower DD, Clements FM, Debruijn NP, Stafford-Smith M, Davis RD, Landolfo KP, Smith PK. Comparison of direct aortic and femoral cannulation for port-access cardiac operations. Ann Thorac Surg. 1999 Oct;68(4):1529-31. (1999) Abstract

Glower DD, Komtebedde J, Clements FM, Debruijn NP, Stafford-Smith M, Newman MF. Direct aortic cannulation for port-access mitral or coronary artery bypass grafting. Ann Thorac Surg. 1999 Nov;68(5):1878-80. (1999) Abstract

Glower DD. Does pregnancy affect the durability of valvular bioprostheses? Am Heart J. 1999 Apr;137(4 Pt 1):590-1. (1999) Abstract

Hochrein J, Lucke JC, Harrison JK, Bashore TM, Wolfe WG, Jones RH, Lowe JE, White WD, Glower DD. Mortality and need for reoperation in patients with mild-to-moderate asymptomatic aortic valve disease undergoing coronary artery bypass graft alone. Am Heart J. 1999 Oct;138(4 Pt 1):791-7. (1999) Abstract

Peterseim DS, Cen YY, Cheruvu S, Landolfo K, Bashore TM, Lowe JE, Wolfe WG, Glower DD. Long-term outcome after biologic versus mechanical aortic valve replacement in 841 patients. J Thorac Cardiovasc Surg. 1999 May;117(5):890-7. (1999) Abstract

Glower DD, Landolfo KP, Cheruvu S, Cen YY, Harrison JK, Bashore TM, Smith PK, Jones RH, Wolfe WG, Lowe JE. Determinants of 15-year outcome with 1,119 standard Carpentier-Edwards porcine valves. Ann Thorac Surg. 1998 Dec;66(6 Suppl):S44-8. (1998) Abstract

Glower DD, Landolfo KP, Clements F, Debruijn NP, Stafford-Smith M, Smith PK, Duhaylongsod F. Mitral valve operation via Port Access versus median sternotomy. Eur J Cardiothorac Surg. 1998 Oct;14 Suppl 1:S143-7. (1998) Abstract

Glower DD, Landolfo KP, Davis RD, Cen YY, Harrison JK, Bashore TM, Lowe JE, Wolfe WG. Comparison of open mitral commissurotomy with mitral valve replacement with or without chordal preservation in patients with mitral stenosis. Circulation. 1998 Nov 10;98(19 Suppl):II120-3. (1998) Abstract

Lucke JC, Samy RN, Atkins BZ, Silvestry SC, Douglas JM Jr, Schwab SJ, Wolfe WG, Glower DD. Results of valve replacement with mechanical and biological prostheses in chronic renal dialysis patients. Ann Thorac Surg. 1997 Jul;64(1):129-32; discussion 132-3. (1997) Abstract

Blair KL, Hatton AC, White WD, Smith LR, Lowe JE, Wolfe WG, Young WG, Oldham HN, Douglas JM Jr, Glower DD. Comparison of anticoagulation regimens after Carpentier-Edwards aortic or mitral valve replacement. Circulation. 1994 Nov;90(5 Pt 2):II214-9. (1994) Abstract

Glower DD, White WD, Hatton AC, Smith LR, Young WG, Wolfe WG, Lowe JE. Determinants of reoperation after 960 valve replacements with Carpentier-Edwards prostheses. J Thorac Cardiovasc Surg. 1994 Feb;107(2):381-92; discussion 392-3. (1994) Abstract

Glower DD, Murrah RL, Olsen CO, Davis JW, Rankin JS. Mechanical correlates of the third heart sound. J Am Coll Cardiol. 1992 Feb;19(2):450-7. (1992) Abstract

Glower DD, Speier RH, White WD, Smith LR, Rankin JS, Wolfe WG. Management and long-term outcome of aortic dissection. Ann Surg. 1991 Jul;214(1):31-41. (1991) Abstract

Glower DD, Fann JI, Speier RH, Morrison L, White WD, Smith LR, Rankin JS, Miller DC, Wolfe WG. Comparison of medical and surgical therapy for uncomplicated descending aortic dissection. Circulation. 1990 Nov;82(5 Suppl):IV39-46. (1990) Abstract

Morris JJ, Smith LR, Glower DD, Muhlbaier LH, Reves JG, Wechsler AS, Rankin JS. Clinical evaluation of single versus multiple mammary artery bypass. Circulation. 1990 Nov;82(5 Suppl):IV214-23. (1990) Abstract

Maier GW, Newton JR Jr, Wolfe JA, Tyson GS Jr, Olsen CO, Glower DD, Spratt JA, Davis JW, Feneley MP, Rankin JS. The influence of manual chest compression rate on hemodynamic support during cardiac arrest: high-impulse cardiopulmonary resuscitation. Circulation. 1986 Dec;74(6 Pt 2):IV51-9. (1986) Abstract

Glower DD, Spratt JA, Snow ND, Kabas JS, Davis JW, Olsen CO, Tyson GS, Sabiston DC Jr, Rankin JS. Linearity of the Frank-Starling relationship in the intact heart: the concept of preload recruitable stroke work. Circulation. 1985 May;71(5):994-1009. (1985) Abstract