Department / Division:
Surgery / Neurosurgery

Address:
DUMC 2624
Durham, NC 27710

Appointment Telephone:
919-698-3152 (Duke patients)
919-286-0411, ext. 7010 (VA patients)

Office Telephone:
919-698-3152 (Duke)
919-286-0411, ext. 7010 (VA)

Fax Telephone:
919-684-5483 (Duke patients), 919-416-5857 (VA patients)

• MD, Johns Hopkins University School of Medicine (Maryland), 1998

• Neurosurgery, Duke University Medical Center, 2005

• Neuro-Oncology, Duke University Medical Center, 2005

• PhD, Neuroscience, Johns Hopkins University (Maryland), 1998
• MPH, Johns Hopkins University (Maryland), 1999
• MHSc, Clinical Trials, Duke University, 2007

Clinical Interests:
General adult neurosurgery with special interests in primary and secondary brain tumors, skull-base tumors, posterior fossa tumors, pituitary tumors, spinal tumors

Research Interests:
Cory directs the Molecular Neuro-Oncology Laboratory, affiliated with the The Preston Robert Tisch Brain Tumor Center at Duke, which aims to identify and explore critical genes in high grade brain tumorigenesis. State-of-the-art genome-wide screening techniques are used to identify novel genes. Associated signaling pathways are then explored in a myriad of tumor in vitro and in vivo models to better characterize key pathways and identify pharmacogenomic targets.

Representative Publications:
Kanu OO, Mehta A, Di C, Lin N, Bortoff K, Bigner DD, Yan H, Adamson DC. Glioblastoma multiforme: a review of therapeutic targets. Expert Opin Ther Targets. 2009 Jun;13(6):701-18. (2009) Abstract

Kanaly CW, Selznick LA, Cummings TJ, Adamson DC. Cerebellar cryptococcoma in a patient with undiagnosed sarcoidosis: case report. Neurosurgery. 2007 Mar;60(3):E571; discussion E571. (2007) Abstract

Di C, Liao S, Adamson DC, Parrett TJ, Broderick DK, Shi Q, Lengauer C, Cummins JM, Velculescu VE, Fults DW, McLendon RE, Bigner DD, Yan H. Identification of OTX2 as a medulloblastoma oncogene whose product can be targeted by all-trans retinoic acid. Cancer Res. 2005 Feb 1;65(3):919-24. (2005) Abstract

Adamson DC, Dimitrov DF, Bronec PR. Upward transtentorial herniation, hydrocephalus, and cerebellar edema in hypertensive encephalopathy. Neurologist. 2005 May;11(3):171-5. (2005) Abstract

Adamson DC, Cummings TJ, Friedman AH. Myxopapillary ependymoma and fatty filum in an adult with tethered cord syndrome: a shared embryological lesion? Case report. Neurosurgery. 2005 Aug;57(2):E373; discussion E373. (2005) Abstract

Samdani AF, Kuchner EB, Rhines L, Adamson DC, Lawson C, Tyler B, Brem H, Dawson VL, Dawson TM. Astroglia induce cytotoxic effects on brain tumors via a nitric oxide-dependent pathway both in vitro and in vivo. Neurosurgery. 2004 May;54(5):1231-7; discussion 1237-8. (2004) Abstract

Adamson DC, Cummings TJ, Friedman AH. Malignant peripheral nerve sheath tumor of the spine after radiation therapy for Hodgkin's lymphoma. Clin Neuropathol. 2004 Sep-Oct;23(5):245-55. (2004) Abstract

Adamson DC, Bulsara K, Bronec PR. Spontaneous cervical epidural hematoma: case report and literature review. Surg Neurol. 2004 Aug;62(2):156-9; discussion 159-60. (2004) Abstract

Adamson DC, McArthur JC, Dawson TM, Dawson VL. Rate and severity of HIV-associated dementia (HAD): correlations with Gp41 and iNOS. Mol Med. 1999 Feb;5(2):98-109. (1999) Abstract

Adamson DC, Kopnisky KL, Dawson TM, Dawson VL. Mechanisms and structural determinants of HIV-1 coat protein, gp41-induced neurotoxicity. J Neurosci. 1999 Jan 1;19(1):64-71. (1999) Abstract

Adamson DC, Wildemann B, Sasaki M, Glass JD, McArthur JC, Christov VI, Dawson TM, Dawson VL. Immunologic NO synthase: elevation in severe AIDS dementia and induction by HIV-1 gp41. Science. 1996 Dec 13;274(5294):1917-21. (1996) Abstract

Adamson DC, Dawson TM, Zink MC, Clements JE, Dawson VL. Neurovirulent simian immunodeficiency virus infection induces neuronal, endothelial, and glial apoptosis. Mol Med. 1996 Jul;2(4):417-28. (1996) Abstract