Department / Division
Radiation Oncology / Radiation Onc-Clinical Sup
Durham, NC 27710
Hodgkin's and non-Hodgkin's lymphoma; multiple myeloma; mycosis fungoides; lung cancer; plural mesothelioma; thymic malignancies
Clinical trials that are currently open include a study of accelerated radiation therapy for locally-advanced thoracic malignancies (non-small cell lung cancer, small cell lung cancer, and inoperable thymic malignancies) in which patients are treated 6 times a week instead of 5 (two treatments on Fridays), using intensity modulated radiation therapy, with the goal of better tumor control with a lower risk of side effects. We also have a study open investigating lower doses of radiation therapy for patients with diffuse large B-cell lymphoma, with the goal of maintaining excellent tumor control but decreasing the risk of long-term side effects of treatment.
I also have an interest in genetic determinants of radiation sensitivity, predictors of local recurrence after surgery for lung cancer, radiation-induced lung injury, and the role of radiation therapy in advanced (stage III-IV) diffuse large B-cell lymphoma and Hodgkin lymphoma.
This faculty member has no reported relationships with industry.
Dorth, JA; Chino, JP; Prosnitz, LR; Diehl, LF; Beaven, AW; Coleman, RE; Kelsey, CR. The impact of radiation therapy in patients with diffuse large B-cell lymphoma with positive post-chemotherapy FDG-PET or gallium-67 scans. Annals of Oncology. 2011;22:405-410. (2011) Abstract
Kelsey, CR; Mukundan, S; Wang, Z; Hahn, CA; Soher, BJ; Kirkpatrick, JP. Assessing neurotoxicity from the low-dose radiation component of radiosurgery using magnetic resonance spectroscopy. Neuro-Oncology. 2010;12:145-152. (2010) Abstract
Higgins, K; Chino, JP; Marks, LB; Ready, N; D'Amico, TA; Clough, RW; Kelsey, CR. Preoperative chemotherapy versus preoperative chemoradiotherapy for stage III (N2) non-small-cell lung cancer. International Journal of Radiation: Oncology - Biology - Physics. 2009;75:1462-1467. (2009) Abstract
Kelsey, CR; Marks, LB; Hollis, D; Hubbs, JL; Ready, NE; D'Amico, TA; Boyd, JA. Local recurrence after surgery for early stage lung cancer: an 11-year experience with 975 patients. Cancer. 2009;115:5218-5227. (2009) Abstract
Kelsey, CR; Kahn, D; Hollis, DR; Miller, KL; Zhou, SM; Clough, RW; Marks, LB. Radiation-induced narrowing of the tracheobronchial tree: an in-depth analysis. Lung Cancer. 2006;52:111-116. (2006) Abstract
Kelsey, CR; Light, KL; Marks, LB. Patterns of failure after resection of non-small-cell lung cancer: implications for postoperative radiation therapy volumes. International Journal of Radiation: Oncology - Biology - Physics. 2006;65:1097-1105. (2006) Abstract