Department / Division
Radiation Oncology /
Radiation Onc-Clinical Sup
Address
DUMC 3085
Durham, NC 27710
Appointment Telephone
919-660-2100
Office Telephone
919-668-5213
Fax Telephone
919-668-7345
Clinical Interests
Hodgkin's and non-Hodgkin's lymphoma, multiple myeloma, mycosis fungoides, lung cancer, plural mesothelioma, thymic malignancies
Research Interests
Clinical trials that are currently open include a study of accelerated radiation therapy for locally-advanced thoracic malignancies (non-small cell lung cancer, small cell lung cancer, and inoperable thymic malignancies) in which patients are treated 6 times a week instead of 5 (two treatments on Fridays), using intensity modulated radiation therapy, with the goal of better tumor control with a lower risk of side effects. We also have a study open investigating lower doses of radiation therapy for patients with diffuse large B-cell lymphoma, with the goal of maintaining excellent tumor control but decreasing the risk of long-term side effects of treatment.
I also have an interest in genetic determinants of radiation sensitivity, predictors of local recurrence after surgery for lung cancer, radiation-induced lung injury, and the role of radiation therapy in advanced (stage III-IV) diffuse large B-cell lymphoma and Hodgkin lymphoma.
This physician has no reported relationships with industry.
Representative Publications
Dorth JA, Chino JP, Prosnitz LR, Diehl LF, Beaven AW, Coleman RE, Kelsey CR. The impact of radiation therapy in patients with diffuse large B-cell lymphoma with positive post-chemotherapy FDG-PET or gallium-67 scans. Ann Oncol. 2010 Aug 9.
(2010)
Abstract
Kelsey CR, Mukundan S Jr, Wang Z, Hahn CA, Soher BJ, Kirkpatrick JP. Assessing neurotoxicity from the low-dose radiation component of radiosurgery using magnetic resonance spectroscopy. Neuro Oncol. 2010 Feb;12(2):145-52.
(2010)
Abstract
Higgins K, Chino JP, Marks LB, Ready N, D'Amico TA, Clough RW, Kelsey CR. Preoperative chemotherapy versus preoperative chemoradiotherapy for stage III (N2) non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2009 Dec 1;75(5):1462-7.
(2009)
Abstract
Kelsey CR, Marks LB, Hollis D, Hubbs JL, Ready NE, D'Amico TA, Boyd JA. Local recurrence after surgery for early stage lung cancer: an 11-year experience with 975 patients. Cancer. 2009 Nov 15;115(22):5218-27.
(2009)
Abstract
Kelsey CR, Kahn D, Hollis DR, Miller KL, Zhou SM, Clough RW, Marks LB. Radiation-induced narrowing of the tracheobronchial tree: an in-depth analysis. Lung Cancer. 2006 Apr;52(1):111-6.
(2006)
Abstract
Kelsey CR, Light KL, Marks LB. Patterns of failure after resection of non-small-cell lung cancer: implications for postoperative radiation therapy volumes. Int J Radiat Oncol Biol Phys. 2006 Jul 15;65(4):1097-105.
(2006)
Abstract
