Director, Duke Heart Center
Executive Director, Cardiology

Department / Division:
Medicine / Cardiology

Address:
DUMC 3356
Durham, NC 27710

Appointment Telephone:
919-681-5816

Office Telephone:
919-681-6195

Fax Telephone:
919-681-7755

• MD, University of Maryland School of Medicine, 1983

• Internal Medicine/Cardiology, Duke University Medical Center, 1983-1986, 1986-1987, 1988-1989

Clinical Interests:
Management of heart failure and chronic ischemic heart disease

Research Interests:
Dr. O'Connor is the principal investigator of "A Randomized Trial of Heparin in Conjunction with Anistreplase in Acute Myocardial Infarction, "also known as the DUCCS I study (1991).  He is also medical director of the National Institutes of Health Silent Ischemia Study (1989); and co-principal investigator of several other cardiology studies sponsored by Dupont, Pfizer, and Andrew W. Mellon Foundation.

Representative Publications:
O'Conor CM, Stroke during acute myocardial infarction. In: Acute Coronary Care; St. Louis, MO, December 1994. (1994)

O'Connor CM, Meese R, Carney R, Smith J, Conn E, Burks J, Hartman C, Roark S, Shasoff N, Heard M, Mittler B, Collins G, Navetta F, Lee K, Califf RM for the Duke University Clinical Cardiology Study Group. A randomized trial of heparin in conjunction with anistreplase APSAC in acute myocardial infarction. The DUCCS 1 Study. JACC 1993;23:11-18. (1993)

O'Connor CM, Califf RM, Massey EW, Mark DB, Kereiakes DJ, Candela RJ, Abbottsmith C, George B, Stack RS, Aronson L, Mantell S, Topol EJ. Stroke and acute myocardial infarction in the thrombolytic era: Clinical Correlates and long-term prognosis. JACC 1990;16:533-40. (1990)

O'Connor CM, Mark DB, Hinohara T, Stack RS, Rendall D, Haltky MA, Pryor DB, Phillips HR, Califf RM. Rescue coronary angioplasty after failure of intravenous streptokinase in acute myocardial infarction: In-hospital and long-term outcomes. J Inv Car 1989;1:85-95. (1989)

Stack RS, O'Connor CM, Mark DB, Hinohara T, Phillips HR, Ramirex NM, O'Callaghan WG, Simonton CA, Carlson EB, Morris KG, Behar VS, Kong Y, Peter RH, Califf RM. Coronary perfusion during acute myocardial infarction with a combined theapy of coronary angioplasty and high dose intravenous streptokinase. Circulation 1988;77(1):151-161. (1988)