Chief, Division of Cardiology
Director, Duke Heart Center
Durham, NC 27710
Management of heart failure; chronic ischemic heart disease
Dr. O’Connor’s research interests include: acute heart failure; co-morbidities in heart failure; clinical trials; biomarkers; and novel pharmacological and non-pharmacological approaches for the treatment of heart failure.
This faculty member (or a member of their immediate family) has a working relationship (i.e. consulting, research, and/or educational services) with the companies listed below. These relations have been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts.
Felker, GM; Lee, KL; Bull, DA; Redfield, MM; Stevenson, LW; Goldsmith, SR; LeWinter, MM; Deswal, A; Rouleau, JL; Ofili, EO; Anstrom, KJ; Hernandez, AF; McNulty, SE; Velazquez, EJ; Kfoury, AG; Chen, HH; Givertz, MM; Semigran, MJ; Bart, BA; Mascette, AM; Braunwald, E; O'Connor, CM; NHLBI Heart Failure Clinical Research Network. Diuretic strategies in patients with acute decompensated heart failure. New England Journal of Medicine. 2011;364:797-805. (2011) Abstract
O'Connor, CM; Starling, RC; Hernandez, AF; Armstrong, PW; Dickstein, K; Hasselblad, V; Heizer, GM; Komajda, M; Massie, BM; McMurray, JJ; Nieminen, MS; Reist, CJ; Rouleau, JL; Swedberg, K; Adams, KF; Anker, SD; Atar, D; Battler, A; Botero, R; Bohidar, NR; Butler, J; Clausell, N; Corbalán, R; Costanzo, MR; Dahlstrom, U; Deckelbaum, LI; Diaz, R; Dunlap, ME; Ezekowitz, JA; Feldman, D; Felker, GM; Fonarow, GC; Gennevois, D; Gottlieb, SS; Hill, JA; Hollander, JE; Howlett, JG; Hudson, MP; Kociol, RD; Krum, H; Laucevicius, A; Levy, WC; Méndez, GF; Metra, M; Mittal, S; Oh, BH; Pereira, NL; Ponikowski, P; Tang, WH; Tanomsup, S; Teerlink, JR; Triposkiadis, F; Troughton, RW; Voors, AA; Whellan, DJ; Zannad, F; Califf, RM. Effect of nesiritide in patients with acute decompensated heart failure. New England Journal of Medicine. 2011;365:32-43. (2011) Abstract
Sherwood, A; Blumenthal, JA; Hinderliter, AL; Koch, GG; Adams, KF; Dupree, CS; Bensimhon, DR; Johnson, KS; Trivedi, R; Bowers, M; Christenson, RH; O'Connor, CM. Worsening depressive symptoms are associated with adverse clinical outcomes in patients with heart failure. Journal of the American College of Cardiology. 2011;57:418-423. (2011) Abstract
O'Connor, CM; Hasselblad, V; Mehta, RH; Tasissa, G; Califf, RM; Fiuzat, M; Rogers, JG; Leier, CV; Stevenson, LW. Triage after hospitalization with advanced heart failure: the ESCAPE (Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness) risk model and discharge score. Journal of the American College of Cardiology. 2010;55:872-878. (2010) Abstract
O'Connor, CM; Jiang, W; Kuchibhatla, M; Silva, SG; Cuffe, MS; Callwood, DD; Zakhary, B; Stough, WG; Arias, RM; Rivelli, SK; Krishnan, R; SADHART-CHF Investigators. Safety and efficacy of sertraline for depression in patients with heart failure: results of the SADHART-CHF (Sertraline Against Depression and Heart Disease in Chronic Heart Failure) trial. Journal of the American College of Cardiology. 2010;56:692-699. (2010) Abstract
Flynn, KE; Piña, IL; Whellan, DJ; Lin, L; Blumenthal, JA; Ellis, SJ; Fine, LJ; Howlett, JG; Keteyian, SJ; Kitzman, DW; Kraus, WE; Miller, NH; Schulman, KA; Spertus, JA; O'Connor, CM; Weinfurt, KP; HF-ACTION Investigators. Effects of exercise training on health status in patients with chronic heart failure: HF-ACTION randomized controlled trial. JAMA: Journal of the American Medical Association. 2009;301:1451-1459. (2009) Abstract
O'Connor, CM; Whellan, DJ; Lee, KL; Keteyian, SJ; Cooper, LS; Ellis, SJ; Leifer, ES; Kraus, WE; Kitzman, DW; Blumenthal, JA; Rendall, DS; Miller, NH; Fleg, JL; Schulman, KA; McKelvie, RS; Zannad, F; Piña, IL; HF-ACTION Investigators. Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial. JAMA: Journal of the American Medical Association. 2009;301:1439-1450. (2009) Abstract
O'Connor, CM; Califf, RM; Massey, EW; Mark, DB; Kereiakes, DJ; Candela, RJ; Abbottsmith, C; George, B; Stack, RS; Aronson, L. Stroke and acute myocardial infarction in the thrombolytic era: clinical correlates and long-term prognosis. Journal of the American College of Cardiology. 1990;16:533-540. (1990) Abstract