Physicians

Medical Director, Acute Pain Therapy

Department / Division
Anesthesiology / Anesthesiology-Regional Division

Address
DUMC 3094
Durham, NC 27710

Appointment Telephone
919-681-5396

Office Telephone
919-681-5396

Fax Telephone
919-681-7901

Training

• MB BCh, University of the Witwatersrand School of Clinical Medicine (South Africa), 1975

Residency

• Anesthesiology, University of the Witwatersrand Faculty of Health Sciences (South Africa), 1979-1983

Clinical Interests
Acute pain, general and pediatric anesthesiology

Research Interests
My research activities, which are totally clinical and are closely intertwined with my clinical endeavors in the fields of acute pain management and pediatric anesthesia.   Research in acute pain management will involve the introduction of both new drugs and techniques into the routine armamentarium of the acute pain team.   Another beneficial avenue of research is the use of non invasive and lower cost technologies such as transmucosal fentanyl in the management of pain states.  Studies will determine dosing equivalence and therapeutic effectiveness of transmucosal fentanyl.  The focus of acute pain therapy is shifting from intermittent analgesia to around the clock medication  The development of slow release formulations of potent opioids allows for the study of these agents to optimize postoperative pain.  Continuous monitoring of the effectiveness of pain therapy is required to justify the time and expense of therapy.  Studies are underway to determine patient satisfaction with these newer modalities of pain care.

One of the clinical challenges in pediatric anesthesia is to overcome some of the trauma associated with pediatric anesthesia.  This entails the use of new pharmacological agents and psychological preparation of children prior to surgery.

Industry Relationships and Collaborations (What's this?)

This physician (or a member of their immediate family) has a working relationship (i.e. consulting, research, and/or educational services) with the companies listed below. These relations have been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts.

• Cadence Pharmaceuticals, Inc.
• Johnson & Johnson
• Pfizer Inc.
• Purdue Pharma L.P.

Representative Publications
Ginsberg B, Dear RB, Margolis JO, Dear GDL, Ross AK: Oral trnasmucosal fentanyl citrate as an anesthetic premedication when dosed to an opioid effect versus total opioid consumption. Pediatric Anesthesia 8(5):413-418, 1998 (1998)

Muir MR, Sullivan FL, Dear G,, Ginsberg B. Monitoring practices following epidural analgesics for pain management: A follow-up survey. Journal of Pain and Symptom Management. 14(1):36-44, 1997 (1997)

Ginsberg B, J, Howell, Glass PSA, Margolis S, Ross AK, Dear G, Shafer S. Pharmacokinetic model driven infusion of fentanyl in chidlren. Anesthesiology 85(6):1268-75, 1996 (1996)

Ginsberg B, Gil KM, Muir MR, Sullivan F, Williams DA, Glass PSA: The influence of lockout interval and drug selection on patient controlled analgesia following gynecological surgery. Pain 62: 95-100,1995. (1995)

Ginsberg B, Glass PS, Ossey KD, Quill T, Shafron D, Ossey K: Onset and duration of neuromuscular blockade following high-dose vecuronium administration. Anesthesiology 71: 201-205, 1989. (1989)