Department / Division
Obstetrics/Gynecology /
Gynecology Oncology
Address
DUMC 3079
Durham, NC 27710
Appointment Telephone
919-684-3765
Office Telephone
919-684-3765
Fax Telephone
919-684-8719
Clinical Interests
Gynecologic malignancies, premalignant diseases of the cervix and vagina, immunotherapy and radiation therapy, radical pelvic surgery, reconstructive pelvic surgery, laser surgery, complicated gynecologic surgery, robot-assisted minimally invasive surgery and laparoscopy, chemotherapy and novel targeted biologic therapy, clinical trials
Research Interests
My primary research interest has focused on angiogenesis, molecular signatures, clinical trial development, and ovarian cancer. My fundamental goal is to develop a strong translational research program at Duke University in the Gynecologic Oncology Division where knowledge we glean from our basic science research can be incorporated into our clinical trial program. Specifically on anti-angiogenic therapy and molecular tumor signatures to direct therapy in patients with ovarian cancer to determine if a strategy that incorporates both clinical and genomic information can improve clinical outcome, minimize unnecessary toxicity, and impact positively on quality of life.
In addition I am interested in robotic-assisted laparoscopic surgery for women with endometrial, ovarian, and cervical cancers as well as for benign gynecologic conditions.
This faculty member has no reported relationships with industry.
Representative Publications
Gynecologic Oncology Group, ; Secord, AA; Lee, PS; Darcy, KM; Havrilesky, LJ; Grace, LA; Marks, JR; Berchuck, A. Maspin expression in epithelial ovarian cancer and associations with poor prognosis: a Gynecologic Oncology Group study. Gynecologic Oncology. 2006;101:390-397.
(2006)
Abstract
