Chief, Division of Pediatric Anesthesia and Critical Care Medicine

• Anesthesiology / Anesthesiology
• Pediatrics / Anesthesiology

Address:
DUMC 3094
Durham, NC 27710

Office Telephone:
919-681-4877

Fax Telephone:
919-684-9894

• MD, Joan C. Edwards School of Medicine at Marshall University (West Virginia), 1988

• Anesthesiology, Johns Hopkins Hospital (Maryland), 1989-1991

• Pediatric Anesthesiology, Johns Hopkins Hospital (Maryland), 1991-1992

Clinical Interests:
Pediatric anesthesia

Research Interests:
    This is my fifteenth year on the faculty at DUMC.  During these years, there was an initial focus of research work on the pharmacokinetics and pharmacodynamics of anesthetic agents in children and now includes the sedation of mentally challenged children as well as pediatric regional anesthesia.
    Industry funding is presently being provided for several multicenter studies and Duke has been an active participant.  I am the PI for Duke on the investigation of the pk and pd of rocuronium in children that will be completed by mid-2007.  Prior years I have been a PI or coPI for investigations in children at Duke for fentanyl, remifentanil, rapacuronium, rocuronium, and ondansetron.  
In addition to the research that involves anesthetic agents, I remain very active in research regarding the sedation of children who are mentally challenged.  By teaming up with members in the psychiatry department at UNC, I have been able to be a coinvestigator in 2 studies that are funded by NIMH involving imaging procedures under sedation in children who are autistic or developmentally delayed.  My presence for the MRI studies in these children is in its seventh year.
Although the above projects offer funding for the department, my main interest continues to be in the area of pediatric regional anesthesia.  Duke anesthesiologists have become well-known for their work in regional anesthesia, and this is true in the pediatric arena as well.  Trials are ongoing and have resulted in many abstracts, papers, and lectures.

Representative Publications:
Ross AK.  Muscular dystrophy versus mitochondrial myopathy: the dilemma of the undiagnosed hypotonic child.  Pediatric Anesthesia 2007; 17: 1-6 (2007)

Ross AK.  Pediatric regional anesthesia: Smith's Anesthesia for Infants and Children.  Pp459-506 Editors Motoyama EK, Davis PJ.  7th ed.  Philadelphia:Mosby: 2006 (2006)

Hazlett HC, Poe M, Gerig G, Smith RG, Provenzale J, Ross A, Piven J.  Magnetic resonance imaging and head circumference study of brain size in autism: birth through age two years.  Archives General Psychiatry 2005; 62: 1366-76 (2005)

Eck JB, Ross AK.  Pediatric regional anesthesia-what makes a difference?  Best practice and research in Clinical Anesthesiology.  2002; 16(2): 159-74. (2002)

Ross AK. Pediatric trauma. Anesthesia management. Anesthesiol Clin North America. 2001 Jun;19(2):309-37. (2001) Abstract

Ross AK, Davis PJ, Dear Gd GL, Ginsberg B, McGowan FX, Stiller RD, Henson LG, Huffman C, Muir KT. Pharmacokinetics of remifentanil in anesthetized pediatric patients undergoing elective surgery or diagnostic procedures. Anesth Analg. 2001 Dec;93(6):1393-401, table of contents. (2001) Abstract

Ross AK, Eck JB, Tobias JD. Pediatric regional anesthesia: beyond the caudal. Anesth Analg. 2000 Jul;91(1):16-26. (2000) Abstract

Ross AK, Dear GL, Dear RB, Margolis JO, Ginsberg B. Onset and recovery of neuromuscular blockade after two doses of rocuronium in children. J Clin Anesth. 1998 Dec;10(8):631-5. (1998) Abstract