Department / Division:
Medicine
/
Neurology
Address:
DUMC 3678
Durham, NC 27710
Appointment Telephone:
(919) 668-7600
Office Telephone:
(919) 681-3448
Fax Telephone:
(919) 684-8955
Clinical Interests:
Epilepsy (medical and surgical treatment), sleep disorders (particularly
hypersomnolence), EEG
Research Interests:
Main focus is in epilepsy, sleep disorders, and clinical neurophysiology interpretation. Specific areas of interest include predictive outcome factors in epilepsy surgery, neuroimaging characteristics of neuronal migration disorders, development of new medical treatments of epilepsy and narcolepsy, and the pharmacogenetics of epilepsy and its treatment.
No involvement in basic laboratory research.
Ongoing clinical trials include:
1) Pharmacogenetics of epilepsy
2) behavioral treatment trial for insomnia
Special expertise recognized by serving on Professional Advisory Board of the Epilepsy Foundation of America and election as chairman of the American Board of Clinical Neurophysiology (certifying body in EEG, Evoked Potentials, Epilepsy Monitoring and Sleep).
Key words: Epilepsy
Epilepsy Surgery
Sleep Disorders
Sleep Apnea
Narcolepsy
Clinical Neurophysiology
Representative Publications:
Lee N, Tien RD, Lewis DV, Friedman AH, Felsberg GJ, Crain B, Hulette C, Osumi AK, VanLandingham KE, Radtke RA. Fast Spin-Echo MRI-measured Absolute Hippocampal Volume: Correlation with Neuronal Density in Temporal Lobectomy Patients. Epilepsia 36(9):899-904, 1995.
(1995)
Radtke RA, Erwin CW, Wilkins RH. Intraoperative Brainstem Evoked Potentials (BAEPs): Significant Decrease in Postoperative Auditory Deficit. Neurology 39:187-192, 1989. Abstracted in: Key Neurology Neurosurgery 1989. Abstracted in Yearbook of Neurology and Neurosurgery 1990.
(1989)
Radtke RA. Sleep Disorders: Laboratory Evaluation. In: Current Practice of Clinical EEG. Pedley TA, Ebersole J (eds, 2002.
Gibbs JW, Ciafaloni E, Radtke RA. Excessive Daytime Somnolence and Increased REM Pressure in Myotonic Dystrophy. Sleep 25(6):672-675, 2002.
(2002)
Radtke RA, Hanson MW, Hoffman JM, Crain BJ, Walczak TS, Lewis DV, Coleman RE, Friedman AH. Temporal Lobe Hypometabolism on PET: Predictor of Seizure Control after Temporal Lobectomy. Neurology 43:1088-92, 1993.
(1993)
Lee N, Radtke RA, Gray L, Burger PC, Montine TJ, DeLong GR, Lewis DV, Oakes WJ, Friedman AH, Hoffman JM. Neuronal Migration Disorders: PET Correlations. Annals of Neurology 35:290-297, 1994.
(1994)
