Rex M. McCallum, MD

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• Rheumatology and Immunology

Associate Medical Director, PDC

Department / Division:
Medicine / Rheumatology and Immunology

Address:
DUMC 2954
Durham, NC 27710

Appointment Telephone:
(919) 668-7630

Office Telephone:
(919) 684-8763

Fax Telephone:
(919) 684-6671

• M.D., Vanderbilt University, Tennessee, 1980

• Internal Medicine, Duke University Medical Center, North Carolina, 1980-1983
• Rheumatology, Duke University Medical Center, North Carolina, 1983-1986

Clinical Interests:
Vasculitis, Cogan's syndrome, rheumatoid arthritis, connective tissue disease, inflammatory eye disease and systemic illnesses

Research Interests:
My main research interests remain Cogan's syndrome, inflammatory eye disease, and vasculitis.  I  maintain a clinical data base of the greater than 50 patients with Cogan's syndrome that have been evaluated by Dr. Barton F. Haynes and me since 1977.  Cogan's syndrome is a syndrome of inflammatory eye disease associated with vestibuloauditory dysfunction that is Menierre's-like.  The etiology of this unusual illness is felt to be inflammatory and autoimmune.  In addition, I am one of two attendings in the Duke Uveitis Clinic with Dr. Glen Jaffe of ophthalmology.  We maintain a clinical data base of all patients evaluated in the clinic.  We perform clinical trials of medications and new approaches to treating inflammatory eye disese.  We use an number of systemic medicines to treat inflammatory eye diseases and evaluate our results.

I am co-principal investigator for my colleague, Dr. E. William St. Clair, on his rheumatoid arthritis trials.


Key words: Cogan's syndrome, vasculitis, inflammatory eye disease, uveitis, rheumatoid arthritis

Representative Publications:
McCallum RM, Haynes BF: Systemic Necrotizing Vasculitis. In Current Therapy in Allergy, Immunology and Rheumatology, 5th Edition, pp. 241-246. Lichtenstein LM, Fauci AS (Editors), Mosby-Year Book, Philadelphia, PA, 1996. (1996)

McCallum RM: Cogan's Syndrome. In Current Therapy in Allergy, Immunology and Rheumatology, 5th Edition, pp. 255- 260. Lichtenstein LM, Fauci AS (Editors), Mosby-Year Book, Philadelphia, PA, 1996. (1996)