John J. Freiberger, MD, MPH

Related Content

Services

• Anesthesiology
• Hyperbaric, Diving, and Altitude Medicine

Department / Division:
Anesthesiology / Anesthesiology

Address:
DUMC 3823
Durham, NC 27710

Appointment Telephone:
919-684-6726

Office Telephone:
919-684-6726

Fax Telephone:
919-684-6002

• MD, University of Texas Southwestern Medical School, 1979

• Anesthesiology, Massachusetts General Hospital, 1983

• Critical Care Medicine, Massachusetts General Hospital, 1984
• Hyperbaric Medicine, Duke University Medical Center, 2001

• MPH, University of North Carolina School of Public Health, 1999

Clinical Interests:
Hyperbaric medicine, diving medicine, neuroprotection and wound healing

Research Interests:
Dr Freiberger works on the translation of basic science research on reactive oxygen species signaling into clinical practice involving hyperbaric oxygen (HBO).  He has performed animal experiments in the use of HBO for ischemic preconditioning and he is currently funded to conduct a randomized controlled trial of the use of HBO for the treatment of bisphosphonate-induced osteonecrosis of the jaw. The mechanisms of action for HBO in the treatment of: diabetic wounds, bony and soft tissue radionecrosis and decompression sickness are also areas of his inquiry.  As the Associate Medical Director for the Diver’s Alert Network Dr Freiberger also does basic epidemiological research into accidents and injuries associated with diving, high altitude exposure and other adverse conditions associated with extreme environments.

Representative Publications:
Longphre JM, Denoble PJ, Moon RE, Vann RD, Freiberger JJ. First aid normobaric oxygen for the treatment of recreational diving injuries.  Undersea Hyperb Med.  2007 Jan-Feb;34(1):43-9. (2007) Abstract

Freiberger JJ, Padilla-Burgos R, Chhoeu AH, Kraft KH, Boneta O, Moon RE, Piantadosi CA. Hyperbaric oxygen treatment and bisphosphonate-induced osteonecrosis of the jaw: a case series.  J Oral Maxillofac Surg.  2007 Jul;65(7):1321-7. (2007) Abstract

Freiberger JJ, Suliman HB, Sheng H, McAdoo J, Piantadosi CA, Warner DS. A comparison of hyperbaric oxygen versus hypoxic cerebral preconditioning in neonatal rats. Brain Res. 2006 Feb 23;1075(1):213-22. (2006) Abstract

Freiberger JJ, Lyman SJ, Denoble PJ, Pieper CF, Vann RD. Consensus factors used by experts in the diagnosis of decompression illness. Aviat Space Environ Med. 2004 Dec;75(12):1023-8. (2004) Abstract

Freiberger J, Lyman S, Denoble PJ, Pieper CF, Vann RD. Consensus factors used by experts in the diagnosis of decompression illness. Aviat Space Environ Med. 2004;75:1023-1028. (2004)

Freiberger J, Coulombe K, Suliman H, Carraway M, Piantadosi C. Superoxide dismutase responds to hyperoxia in rat hippocampus. Undersea Hyperb Med. 2004 Summer;31(2):227-32. (2004) Abstract

Cronje FJ, Carraway MS, Freiberger JJ, Suliman HB, Piantadosi CA. Carbon monoxide actuates o(2)-limited heme degradation in the rat brain. Free Radic Biol Med. 2004 Dec 1;37(11):1802-12. (2004) Abstract

Freiberger JJ, Denoble PJ, Pieper CF, Uguccioni DM, Pollock NW, Vann RD. The relative risk of decompression sickness during and after air travel following diving. Aviat Space Environ Med. 2002 Oct;73(10):980-4. (2002) Abstract