Department / Division:
Medicine
/
Nephrology
Address:
DUMC 3014
Durham, NC 27710
Appointment Telephone:
919-668-7630
Office Telephone:
919-660-6858
Fax Telephone:
919-684-4476
Clinical Interests:
Renal transplantation
Research Interests:
Ongoing work focuses on problems of immediate clinical relevance in renal and pancreas transplantation, including issues related to immunosuppression, infection, and cardiovascular events as well as hypertension.
Research methodologies employed include randomized clinical trials, cohort studies, and retrospective multivariable analyses based on the transplant database.
Current studies include multiple industry sponsored immunosuppressive agent trials and the NIH sponsored FAVORIT trial, a prospective randomized clinical trial of B vitamins in renal transplant recipients with high homocysteine levels. The primary outcome for this trial is a composite of vascular events. The trial has complted enrollment and is in the follow up phase.
Representative Publications:
Lehrich RW, Pun PH, Tanenbaum ND, Smith SR, Middleton JP. Automated external defibrillators and survival from cardiac arrest in the outpatient hemodialysis clinic. J Am Soc Nephrol. 2007 Jan;18(1):312-20.
(2007)
Abstract
Plumb TJ, Greenberg A, Smith SR, Butterly DW, Pham TT, Fields TA, Howell DN. Postinfectious glomerulonephritis in renal allograft recipients. Transplantation. 2006 Nov 15;82(9):1224-8.
(2006)
Abstract
Lehrich RW, Rocha PN, Reinsmoen N, Greenberg A, Butterly DW, Howell DN, Smith SR. Intravenous immunoglobulin and plasmapheresis in acute humoral rejection: experience in renal allograft transplantation. Hum Immunol. 2005 Apr;66(4):350-8.
(2005)
Abstract
Rocha PN, Plumb TJ, Miller SE, Howell DN, Smith SR. Risk factors for BK polyomavirus nephritis in renal allograft recipients. Clin Transplant. 2004 Aug;18(4):456-62.
(2004)
Abstract
Kurella M, Butterly DW, Smith SR. Post transplant erythrocytosis in hypercalcemic renal transplant recipients. Am J Transplant. 2003 Jul;3(7):873-7.
(2003)
Abstract
Smith SR, Butterly DW. Declining influence of race on the outcome of living-donor renal transplantation. Am J Transplant. 2002 Mar;2(3):282-6.
(2002)
Abstract