Stephen R. Smith, MD, MHS

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Services

• Kidney Care
• Transplants

Department / Division:
Medicine / Nephrology

Address:
DUMC 3014
Durham, NC 27710

Appointment Telephone:
(919) 668-7630

Office Telephone:
(919) 660-6858

Fax Telephone:
(919) 684-4476

• M.D., Duke University School of Medicine, North Carolina, 1985

• Internal Medicine, Duke University Medical Center, North Carolina, 1985-1988
• Nephrology, Duke University Medical Center, North Carolina, 1988-1991

• M.H.S., Duke University, North Carolina, 1994

Clinical Interests:
Renal transplantation

Research Interests:
Ongoing work focuses on problems of immediate clinical relevance in renal and pancreas transplantation, including issues related to immunosuppression, infection, and cardiovascular events as well as hypertension.

Research methodologies employed include randomized clinical trials, cohort studies, and retrospective multivariable analyses based on the transplant database.

Current studies include multiple industry sponsored immunosuppressive agent trials and the NIH sponsored FAVORIT trial, a prospective randomized clinical trial of B vitamins in renal transplant recipients with high homocysteine levels.  The primary outcome for this trial is a composite of vascular events.  The trial has complted enrollment and is in the follow up phase.

Representative Publications:
Lehrich RW, Pun PH, Tanenbaum ND, Smith SR, Middleton JP. Automated external defibrillators and survival from cardiac arrest in the outpatient hemodialysis clinic. J Am Soc Nephrol. 2007 Jan;18(1):312-20. (2007) Abstract

Plumb TJ, Greenberg A, Smith SR, Butterly DW, Pham TT, Fields TA, Howell DN. Postinfectious glomerulonephritis in renal allograft recipients. Transplantation. 2006 Nov 15;82(9):1224-8. (2006) Abstract

Lehrich RW, Rocha PN, Reinsmoen N, Greenberg A, Butterly DW, Howell DN, Smith SR. Intravenous immunoglobulin and plasmapheresis in acute humoral rejection: experience in renal allograft transplantation. Hum Immunol. 2005 Apr;66(4):350-8. (2005) Abstract

Rocha PN, Plumb TJ, Miller SE, Howell DN, Smith SR. Risk factors for BK polyomavirus nephritis in renal allograft recipients. Clin Transplant. 2004 Aug;18(4):456-62. (2004) Abstract

Kurella M, Butterly DW, Smith SR. Post transplant erythrocytosis in hypercalcemic renal transplant recipients. Am J Transplant. 2003 Jul;3(7):873-7. (2003) Abstract

Smith SR, Butterly DW. Declining influence of race on the outcome of living-donor renal transplantation. Am J Transplant. 2002 Mar;2(3):282-6. (2002) Abstract