John P. Kirkpatrick, MD, PhD

Related Content

Locations

• Duke Radiation Oncology of Raleigh

Services

• Bone and Soft Tissue Cancer
• Brain Tumors
• Breast Cancer
• Gastrointestinal Cancer
• Head and Neck Cancer
• Lung Cancer
• Skin Cancer

Department / Division:
Radiation Oncology / Radiation Oncology

Address:
DUMC 3085
Durham, NC 27710

Appointment Telephone:
919-660-2100

Office Telephone:
919-668-5213

Fax Telephone:
919-668-7345

• MD, University of Texas School of Medicine at San Antonio, 1999

• Internal Medicine, UNC Hospitals, 1999-2000
• Radiation Oncology, Duke University Medical Center, 2000-2004

• PhD, Chemical Engineering, Rice University (Texas), 1979

Clinical Interests:
Radiation oncology, particularly the treatment of cancers and benign tumors of the central nervous system, base of skull and head/neck; stereotactic radiosurgery, stereotactic radiotherapy and other highly conformal techniques employing spatiotemporal optimization

Representative Publications:
Yin FF, Das S, Kirkpatrick J, Oldham M, Wang Z, Zhou SM. Physics and imaging for targeting of oligometastases. Semin Radiat Oncol. 2006 Apr;16(2):85-101. (2006) Abstract

Soper JT, Spillman M, Sampson JH, Kirkpatrick JP, Wolf JK, Clarke-Pearson DL. High-risk gestational trophoblastic neoplasia with brain metastases: Individualized multidisciplinary therapy in the management of four patients. Gynecol Oncol. 2006 Nov 28. (2006) Abstract

Oldham M, Sakhalkar H, Oliver T, Wang YM, Kirkpatrick J, Cao Y, Badea C, Johnson GA, Dewhirst M. Three-dimensional imaging of xenograft tumors using optical computed and emission tomography.  Med Phys.  2006 Sep;33(9):3193-202. (2006) Abstract

Meyer JJ, Marks LB, Halperin EC, Kirkpatrick JP. Kinetic modeling of tumor growth and dissemination in the craniospinal axis: implications for craniospinal irradiation. Radiat Oncol. 2006;1:48. (2006) Abstract

Koontz BF, Kirkpatrick JP, Clough RW, Prosnitz RG, Gockerman JP, Moore JO, Prosnitz LR. Combined-modality therapy versus radiotherapy alone for treatment of early-stage Hodgkin's disease: cure balanced against complications. J Clin Oncol. 2006 Feb 1;24(4):605-11. (2006) Abstract

Kirkpatrick JP. Tumor hypoxia and prognosis in human gliomas. Cancer J. 2006 Nov-Dec;12(6):451-4. (2006) Abstract

Kirkpatrick JP, Hardee ME, Snyder SA, Peltz CM, Zhao Y, Brizel DM, Dewhirst MW, Blackwell KL. The effect of darbepoetin alfa on growth, oxygenation and radioresponsiveness of a breast adenocarcinoma. Radiat Res. 2006 Feb;165(2):192-201. (2006) Abstract

Kirkpatrick JP, Anscher MS. Radiotherapy for locally recurrent prostate cancer. Clin Adv Hematol Oncol. 2005 Dec;3(12):933-42. (2005) Abstract

Hardee ME, Kirkpatrick JP, Shan S, Snyder SA, Vujaskovic Z, Rabbani ZN, Dewhirst MW, Blackwell KL. Human recombinant erythropoietin (rEpo) has no effect on tumour growth or angiogenesis. Br J Cancer. 2005 Dec 12;93(12):1350-5. (2005) Abstract

Zhang X, Kon T, Wang H, Li F, Huang Q, Rabbani ZN, Kirkpatrick JP, Vujaskovic Z, Dewhirst MW, Li CY. Enhancement of hypoxia-induced tumor cell death in vitro and radiation therapy in vivo by use of small interfering RNA targeted to hypoxia-inducible factor-1alpha. Cancer Res. 2004 Nov 15;64(22):8139-42. (2004) Abstract

Kirkpatrick JP, Marks LB. Modeling killing and repopulation kinetics of subclinical cancer: direct calculations from clinical data. Int J Radiat Oncol Biol Phys. 2004 Feb 1;58(2):641-54. (2004) Abstract

Kirkpatrick JP, Cárdenas-Navia LI, Dewhirst MW. Predicting the effect of temporal variations in PO2 on tumor radiosensitivity. Int J Radiat Oncol Biol Phys. 2004 Jul 1;59(3):822-33. (2004) Abstract

Kirkpatrick JP, Brizel DM, Dewhirst MW. A mathematical model of tumor oxygen and glucose mass transport and metabolism with complex reaction kinetics. Radiat Res. 2003 Mar;159(3):336-44. (2003) Abstract

Kang SK, Kirkpatrick JP, Halperin EC. Low-dose radiation for posttransplant lymphoproliferative disorder. Am J Clin Oncol. 2003 Apr;26(2):210-4. (2003) Abstract

Blackwell KL, Kirkpatrick JP, Snyder SA, Broadwater G, Farrell F, Jolliffe L, Brizel DM, Dewhirst MW. Human recombinant erythropoietin significantly improves tumor oxygenation independent of its effects on hemoglobin. Cancer Res. 2003 Oct 1;63(19):6162-5. (2003) Abstract

Kirkpatrick JP, McIntire LV, Moake JL, Peterson DM. Metabolic requirements of contractile force generation in platelet rich plasma - a rheological study. Biorheology. 1980;17(5-6):411-8. (1980) Abstract

Kirkpatrick JP, McIntire LV, Moake JL, Cimo PL. Differential effects of cytochalasin B on platelet release, aggregation and contractility: evidence against a contractile mechanism for the release of platelet granular contents. Thromb Haemost. 1980 Feb 29;42(5):1483-9. (1980) Abstract

Kirkpatrick JP, McIntire LV, Moake JL. Streptokinase-induced degradation of crosslinked and uncrosslinked clots. Thromb Res. 1978 Sep;13(3):569-75. (1978) Abstract