Home > Physicians > Martin, Paul L.

Paul L. Martin, MD, PhD

Department / Division:
Pediatrics / Blood and Marrow Transplantation

Address:
DUMC 3350
Durham, NC 27710

Appointment Telephone:
(919) 668-1100

Office Telephone:
(919) 668-1124

Fax Telephone:
(919) 668-1180

Training:
  • M.D., Ph.D., Washington University School of Medicine, Missouri, 1987

Residency:
  • Pediatrics, Yale-New Haven Hospital, Connecticut, 1987-1989

Fellowship:
  • Pediatric Hematology-Oncology, Yale University School of Medicine, Connecticut, 1989-1992

Clinical Interests:
Pediatric oncology, pediatric leukemia, stem cell transplantation, infections in immunocompromised patients

Research Interests:
Stem cell transplant for pediatric malignancies.  Treatment of acute lymphoblastic leukemia.  Prevention and treatment of transplant related morbidity, particularly veno-occlusive disease of the liver, infections and pulmonary hemorrhage.

Representative Publications:
Duffner PK, Burger PC, Cohen ME, Sanford RA, Krisher JP, Elterman R, Aronin PA, Pullen J, Horowitz ME, Parent A, Martin PL, Kun LE. Desmoplastic infantile gangliogliomas: an approach to therapy. Neurosurgery 1994; 34:583-589. (1994)

White MS, Martin PL, McLean TW. Acute myelogenous leukemia associated with Ollier disease.  Pediatr Blood Cancer.  ePublished 2006 Sep 21. (2006) Abstract

Safford SD, Safford KM, MARTIN PL, Rice H, Kurtzberg J, Skinner MA.  Management of cholelithiasis in pediatric patients who undergo bone marrow transplantation.  J of Pediatric Surgery  36(1):86-90, 2001. (2001)

MARTIN PL.  The Anemias in Oski’s Pediatrics, Principles and Practice  (Julia A McMillan, Feigin RD, DeAngelis C and Jones MD, editors) 4th ed, JB Lippincott.  pp 1692-1710, 2006. (2006)

Chauvenet AR, Martin PL, Devidas M, Bell BA, Kurtzberg J, Pullen J, Pettenati MJ, Carroll AJ, Shuster JJ, and Camitta B.  Anti-metabolite therapy for lesser risk B-lineage acute lymphoblastic leukemia of childhood: a report from Children's Oncology Group Study P9201.  Blood 2007 in press. (2007)

Martin PL, Carter SL, Kernan NA, Sahdev I, Wall D, Pietryga D, Wagner JE, Kurtzberg J. Results of the cord blood transplantation study (COBLT): outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with lysosomal and peroxisomal storage diseases. Biol Blood Marrow Transplant. 2006 Feb;12(2):184-94. (2006) Abstract

Quaranta BP, Halperin EC, Kurtzberg J, Clough R, Martin PL. The incidence of testicular recurrence in boys with acute leukemia treated with total body and testicular irradiation and stem cell transplantation. Cancer. 2004 Aug 15;101(4):845-50. (2004) Abstract

Borowitz MJ, Pullen DJ, Winick N, Martin PL, Bowman WP, Camitta B. Comparison of diagnostic and relapse flow cytometry phenotypes in childhood acute lymphoblastic leukemia: implications for residual disease detection: a report from the children's oncology group. Cytometry B Clin Cytom. 2005 Nov;68(1):18-24. (2005) Abstract

Richardson PG, Murakami C, Jin Z, Warren D, Momtaz P, Hoppensteadt D, Elias AD, Antin JH, Soiffer R, Spitzer T, Avigan D, Bearman SI, Martin PL, Kurtzberg J, Vredenburgh J, Chen AR, Arai S, Vogelsang G, McDonald GB, Guinan EC. Multi-institutional use of defibrotide in 88 patients after stem cell transplantation with severe veno-occlusive disease and multisystem organ failure: response without significant toxicity in a high-risk population and factors predictive of outcome. Blood. 2002 Dec 15;100(13):4337-43. (2002) Abstract

Wainwright MS, Martin PL, Morse RP, Lacaze M, Provenzale JM, Coleman RE, Morgan MA, Hulette C, Kurtzberg J, Bushnell C, Epstein L, Lewis DV. Human herpesvirus 6 limbic encephalitis after stem cell transplantation. Ann Neurol. 2001 Nov;50(5):612-9. (2001) Abstract

Steinbach WJ, Schell WA, Miller JL, Perfect JR, Martin PL. Fatal Scopulariopsis brevicaulis infection in a paediatric stem-cell transplant patient treated with voriconazole and caspofungin and a review of Scopulariopsis infections in immunocompromised patients. J Infect. 2004 Jan;48(1):112-6. (2004) Abstract

Hall JG, Martin PL, Wood S, Kurtzberg J. Unrelated umbilical cord blood transplantation for an infant with beta-thalassemia major. J Pediatr Hematol Oncol. 2004 Jun;26(6):382-5. (2004) Abstract

Benjamin DK Jr, Miller WC, Bayliff S, Martel L, Alexander KA, Martin PL. Infections diagnosed in the first year after pediatric stem cell transplantation. Pediatr Infect Dis J. 2002 Mar;21(3):227-34. (2002) Abstract

Hagen SA, Craig DM, Martin PL, Plumer DD, Gentile MA, Schulman SR, Cheifetz IM. Mechanically ventilated pediatric stem cell transplant recipients: effect of cord blood transplant and organ dysfunction on outcome. Pediatr Crit Care Med. 2003 Apr;4(2):206-13. (2003) Abstract

Staba SL, Escolar ML, Poe M, Kim Y, Martin PL, Szabolcs P, Allison-Thacker J, Wood S, Wenger DA, Rubinstein P, Hopwood JJ, Krivit W, Kurtzberg J. Cord-blood transplants from unrelated donors in patients with Hurler's syndrome. N Engl J Med. 2004 May 6;350(19):1960-9. (2004) Abstract

Barker JN, Martin PL, Coad JE, DeFor T, Trigg ME, Kurtzberg J, Weisdorf DJ, Wagner J. Low incidence of Epstein-Barr virus-associated posttransplantation lymphoproliferative disorders in 272 unrelated-donor umbilical cord blood transplant recipients. Biol Blood Marrow Transplant. 2001;7(7):395-9. (2001) Abstract

Graham ML, Asselin BL, Herndon JE 2nd, Casey JR, Chaffee S, Ciocci GH, Daeschner CW, Davis AR, Gold S, Halperin EC, Laughlin MJ, Martin PL, Olson JF, Kurtzberg J. Toxicity, pharmacology and feasibility of administration of PEG-L-asparaginase as consolidation therapy in patients undergoing bone marrow transplantation for acute lymphoblastic leukemia. Bone Marrow Transplant. 1998 May;21(9):879-85. (1998) Abstract

Martin PL. To stop or not to stop: how much support should be provided to mechanically ventilated pediatric bone marrow and stem cell transplant patients? Respir Care Clin N Am. 2006 Sep;12(3):403-19. (2006) Abstract

Martin PL, Rappeport JM. Bone marrow transplantation in the perinatal period. Semin Perinatol. 1990 Oct;14(5):416-22. (1990) Abstract

Martin PL, Look AT, Schnell S, Harris MB, Pullen J, Shuster JJ, Carroll AJ, Pettenati MJ, Rao PN. Comparison of fluorescence in situ hybridization, cytogenetic analysis, and DNA index analysis to detect chromosomes 4 and 10 aneuploidy in pediatric acute lymphoblastic leukemia: a Pediatric Oncology Group study. J Pediatr Hematol Oncol. 1996 May;18(2):113-21. (1996) Abstract

Howrey RP, Martin PL, Driscoll T, Szabolcs P, Kelly T, Shpall EJ, Bearman SI, Slat-Vasquez V, Rubinstein P, Stevens CE, Kurtzberg J. Graft-versus-leukemia-induced complete remission following unrelated umbilical cord blood transplantation for acute leukemia. Bone Marrow Transplant. 2000 Dec;26(11):1251-4. (2000) Abstract