Katherine L. Grichnik, MD

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Services

• Anesthesiology

Department / Division:
Anesthesiology / Anesthesiology

Address:
DUMC 3094
Durham, NC 27710

Appointment Telephone:
919-681-6893

Office Telephone:
919-681-6893

Fax Telephone:
919-681-8994

• MD, Tufts University School of Medicine, Massachusetts, 1987

• Anesthesiology, Brigham and Women's Hospital, Massachusetts, 1988-1991

• Pain Management, Brigham and Women's Hospital, Massachusetts, 1990
• Thoraco-Vascular Anesthesia, Brigham and Women's Hospital, Massachusetts, 1991

Clinical Interests:
Cardiothoracic anesthesiology, general anesthesiology, transesophageal echocardiography

Research Interests:
My areas of research support investigation into the optimal perioperative care of the cardiothoracic patient, predictors of CAD, perioperative cognition, adverse outcomes after surgery and oxygen therapeutic research.  This includes supporting trials of novel pharmaceutical agents, or devices to improve outcomes.  I am also involved in a long-term departmental effort to study the effects of anesthesia and surgery in the geriatric patient, especially with respect to effects on pulmonary function, cognition, benefits of regional versus general anesthesia, coagulation and quality of life.  Nationally, I am a member of the National Emphysema Treatment Trial group. I am also undertaking research to investigate the optimal methods for education of the practicing physician, especially to assess teh efficacy of an educational intervention.  

Representative Publications:
Swaminathan M, Shaw AD, Greenfield RA, Grichnik KP.  Fatal Thrombosis after Factor Seven Administration during Extracorporeal Membrane Oxygenation  J Cardiothoracic Vasc Anesth, 21(6);2007 (2007)

Wright MC, Phillips-Bute, B, Mark JB, Stafford-Smith M, Grichnik KP, Andregg BC, Taekman JM. Time of Day Effects on the Incidence of Anesthetic Adverse Events"   Quality and Safety in Health Care, 2006;15:258-63
(2006)

Grichnik KP, Clark JA. Pathophysiology and management of one-lung ventilation. Thorac Surg Clin. 2005 Feb;15(1):85-103. (2005) Abstract

Grichnik KP, D'Amico TA. Acute lung injury and acute respiratory distress syndrome after pulmonary resection. Semin Cardiothorac Vasc Anesth. 2004 Dec;8(4):317-34. (2004) Abstract

Grichnik KP, Hill SE. The perioperative management of patients with severe emphysema. J Cardiothorac Vasc Anesth. 2003 Jun;17(3):364-87. (2003) Abstract

Grichnik KP, Ijsselmuiden AJ, D'Amico TA, Harpole DH Jr, White WD, Blumenthal JA, Newman MF. Cognitive decline after major noncardiac operations: a preliminary prospective study. Ann Thorac Surg. 1999 Nov;68(5):1786-91. (1999) Abstract