Richard A. Leder, MD

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Services

• Radiology

Department / Division:
Radiology / Abdominal Imaging

Address:
DUMC 3808
Durham, NC 27710

Appointment Telephone:
(919) 684-2711

Office Telephone:
(919) 684-7310

Fax Telephone:
(919) 684-7123

• M.D., Boston University School of Medicine, Massachusetts, 1984

• Diagnostic Radiology, State University of New York at Stony Brook, 1984-88

• Abdominal Imaging, Duke University Medical Center, North Carolina, 1988-89

Clinical Interests:
CT/US/MR, oncologic imaging, genitourinary radiology, neoplasms of the upper urinary tract, renal infectious disease, abdominal trauma, contrast media toxicity/reactions

Research Interests:
Current and ongoing research activities include evaluation of contrast reactions in patients who have received a steroid preparation.  This endeavor will aim to evaluate common risk factors shared by patients who have so called breakthrough reactions.  This may help to further redefine premedications regiments in high risk patients.  Additional research activities include clinical CT scanning of the kidneys with the use of a compression device.  The aim of this work will help to establish whether compression CT improves visualization of the collecting system and ureters over conventional urography.  Potentially 3-D reconstructed images may be equivalent or better than conventional urography for filling defects.  Other ongoing projects include CT descriptions of idiopathic retroperitoneal fibrosis causing renal and perirenal masses, post traumatic  pseudopneumoperitoneum and continued work on extravastion injuries and extravasation detection.

Representative Publications:
2. Leder RA, Dunnick NR. Transitional Cell Carcinoma of the Pelvicalices and Ureter. AJR 155:713-722, 1990. (1990)

3. Debatin JF, Cohan RH, Leder RA, Dunnick NR. Selective use of low-osmolar contrast media. Invest Radiol 26: 17-21, 1991. (1991)

1. Cohan RH, Leder RA, Bolick D, Herzberg AJ, Hedlund LW, Wheeler CT, Helms MJ, Dunnick NR. Extravasation of Radiographic Contrast Media: Effects of Conventional and Low-Osmolar Agents in the Rat Thigh. Invest Radiol 25:504-510, 1990. (1990)

4. Dunnick NR, Leight GS Jr, Roubidoux MA, Leder RA, Paulson EK, Kurylo L. CT in the diagnosis of primary aldosteronism: Sensitivity in 29 patients. AJR 160: 321-324, 1993. (1993)

5. Cohan RH, Siegel CL, Korobkin M, Stanley JC, Alpern MB, Courneya DL, Leder RA. CT evaluation of renal artery involvement in patients with ruptured abdominal aortic aneurysms. Radiology 194: 751-756, 1995. (1995)