Brian P. Vickery, MD

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Locations

• Duke Asthma, Allergy and Airway Center
• Duke Children's Hospital & Health Center

Services

• Asthma and Allergies

Department / Division:
Pediatrics / Allergy and Immunology

Address:
DUMC 2644
Durham, NC 27710

Appointment Telephone:
919-684-9914

Office Telephone:
919-681-2949

Fax Telephone:
919-668-3750

• MD, Medical College of Georgia School of Medicine, 2001

• Pediatrics, New York-Presbyterian Hospital, Cornell Campus, 2001-2005

• Allergy and Clinical Immunology, Yale University School of Medicine (Connecticut), 2005-2008

Clinical Interests:
Care of all children with allergic and immunologic disorders, especially food allergy, atopic dermatitis, and anaphylaxis

Research Interests:
I am interested in the relevant mechanistic and clinical aspects of the rising prevalence in atopic disorders. Of particular concern is the relatively recent surge in IgE-mediated and non-IgE mediated food hypersensitivity. During fellowship, my research in the laboratory of Professor Kim Bottomly focused on the role of Toll-like receptor signaling in the dendritic cell response to peanut allergens. This work was part of a larger effort within the Consortium for Food Allergy Research (CoFAR) to develop innovative treatments for IgE-mediated human food allergy. Here at Duke, I am continuing that effort as part of Dr. Wesley Burks' research team, concentrating on oral immunotherapy for food allergy in children. A broader long term goal is to understand the immunologic changes that occur in the development of tolerance, in order to develop strategies for prevention.

In addition, I am currently participating in a multicenter trial of reslizumab, a novel anti-interleukin-5 monoclonal antibody, for the treatment of eosinophilic esophagitis in children 5-18 as well as the American Lung Association Study of Acid Reflux in Children with Asthma (SARCA).

Representative Publications:
Vickery BP. Skin barrier function in atopic dermatitis. Curr Opin Pediatr. 2007 Feb;19(1):89-93. (2007) Abstract