Matthew T. Roe, MD, MHS

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Services

• Emergency Services
• General and Consultative Heart Care

Department / Division:
Medicine / Cardiovascular Medicine

Address:
DUMC 3850
Durham, NC 27710

Appointment Telephone:
919-681-5816

Office Telephone:
919-668-8959

Fax Telephone:
919-668-7059

• MD, Duke University School of Medicine, 1989-1993

• Internal Medicine, Duke University Medical Center, 1993-1996
• Cardiology, Cleveland Clinic Foundation, Ohio, 1996-1999

Clinical Interests:
Cardiovascular disease, acute coronary syndrome

Research Interests:
1) Acute Coronary Syndromes
- Risk Stratification in the Emergency Department
- Optimal Use of Anti-Platelet and Anti-Thrombotic Therapies
- Timing of Treatment with Platelet GP IIb/IIIa Inhibitors
- Early Invasive Management Treatment Strategies

2) Reperfusion Strategies for Acute Myocardial Infarction
- Using Biomarker Arrays to Evaluate Therapies in Phase II Trials
- Combination Reperfusion Therapy with Partial-Dose Fibrinolytics and GP IIb/IIIa Inhibitors

Representative Publications:
4. Roe MT, Ohman EM, Maas ACP, Christenson RH, Mahaffey KW, Granger CB, Harrington RA, Califf RM, Krucoff MW. Shifting the open artery hypothesis downstream: the quest for optimal reperfusion. Journal of the American College of Cardiology 2001;37:9-18. (2001)

3. Roe MT, Harrington RA, Prosper DM, Bhatt DL, Lincoff AM, Simoons ML, Akkerhuis M, Ohman EM, Pieper KS, Kitt MM, Vahanian A, Ruzyllo W, Karsch K, Califf RM, Topol EJ. Clinical and therapeutic profile of patients with acute coronary syndromes who do not have significant coronary artery disease. Circulation 2000;102:1101-1106. (2000)

2. Roe MT, Giugliano RP, Harrington RA, Gibson CM, Strony J, Kitt MM, Califf RM, Braunwald E. Combination reperfusion therapy for acute myocardial infarction with eptifibatide and teneteplase. Design and methodology of the (INTEGRILIN and tenecteplase in acute myocardial infarction) INTEGRITI trial. Heart Drug 2000;1:5-13. (2000)

1. Roe MT, Treatment Strategies for Microvascular Dysfunction Following Acute Myocardial Infarction. Current Cardiology Reports 2000; 2:405 - 410. (2000)