Robert A. Harrington, MD

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Services

• Emergency Services
• General and Consultative Heart Care

Department / Division:
Medicine / Cardiovascular Medicine

Address:
2400 Pratt Street, Room 7007
Durham, NC 27705

Appointment Telephone:
(919) 681-5816

Office Telephone:
(919) 668-8749

Fax Telephone:
(919) 668-7072

• M.D., Tufts University School of Medicine, Massachusetts, 1986

• Internal Medicine, University of Massachusetts Medical Center, 1986-1990
• Cardiology, Duke University Medical Center, North Carolina, 1990-1993

Clinical Interests:
Interventional cardiology (PTCA), ischemic heart disease, acute coronary care, cardiovascular clinical trials

Research Interests:
Robert A. Harrington, MD is a faculty member in the Duke Clinical Research Institute where he is the Director of Cardiovascular Clinical Trials.  His main research interests are in evaluating antithrombotic therapies to treat acute ischemic heart disease and to minimize the acute complications of percutaneous coronary procedures.  He is actively involved in studying the mechanism of disease of the acute coronary syndromes, in understanding the issues of risk stratification in the care of patients with acute ischemic coronary syndromes and in trying to better understand and improve upon the methodology of large clinical trials.  Dr. Harrington has served as one of the principal investigators on several of the largest randomized clinical trials conducted with acute coronary syndrome patients including PURSUIT, PARAGON B, and SYMPHONY in addition to serving as an investigator on several others.  The findings of these studies have been published in some of medicine’s most prestigious journals including the New England Journal of Medicine, JAMA, and Circulation.

Dr. Harrington’s expertise in the methodology of such large, complex, international trials has provided his recent trainees with opportunities to participate in every facet of randomized clinical trials, from protocol development and approval, recruitment of sites and patients, enrollment issues, coordination of activities with sponsors, presentation of results and manuscript publication as well as the FDA drug approval process.  As the current Director of the DCRI’s Cardiovascular Clinical Trials, he remains in a unique position to provide trainees with opportunities in all phases of a clinical trial’s operations.  Dr. Harrington began acting as a mentor just one year after his appointment to the Duke faculty, and severak of his trainees have already gone on to academic appointments.  Dr. Harrington reports directly to Dr. Califf.