Department / Division:
Pathology
/
Pathology
Address:
DUMC 3712
Durham, NC 27710
Office Telephone:
(919) 668-2177
Fax Telephone:
(919) 681-1577
Clinical Interests:
Renal pathology; transplantation
Research Interests:
The primary research interests of my laboratory revolve around understanding transmembrane signaling pathways regulated by the family of heterotrimeric guanine nucleotide binding proteins known as G proteins. There are two main areas of focus. First, we are interested in understanding the impact of G proteins and G protein coupled signaling on pathways that are not traditionally thought to be regulated by these GTP-binding proteins. The second major focus is understanding the role of specific G proteins in tumor biology, especially tumor progression and metastasis.
