Eligibility Requirements

The Duke Center for Human Genetics is actively recruiting families who have two or more family members with Chiari type I malformations (CMI), with or without syringomyelia. These family members must be related to each other by blood and both must be willing to participate.

Our work is centered on determining whether or not there is a genetic cause to the development of CMI. Hopefully in the future this will lead to better ways to diagnose and treat CMI.

Study Requirements

Participation in the study involves:

• Read and sign consent forms
• Provide a blood sample from family members both with and without CMI
• Participate in a family history telephone interview
• Complete a medical history questionnaire
• Review medical records and MRIs to confirm the diagnosis of CMI/S

For more information, contact the study coordinator at chiari@chg.duhs.duke.edu or call at 1-877-825-1694.