The purpose of the study is to continue evaluation and monitoring of the safety and effectiveness of a new device to repair the mitral valve. The device is called the MitraClip System.

Eligibility Requirements

Participants must:

• Have been diagnosed with grade three (moderate to severe) or grade four (severe) mitral regurgitation (MR)
• Be symptomatic
• Be seeking treatment for their condition
• Be a candidate for mitral valve surgery
• Be at least 18 years of age
• Have appropriate valve anatomy

Study Requirements

Participants must:

• Have a medical history review
• Have physical exams
• Have a blood test
• Have a transesophageal echocardiogram
• Be available for up to five years of clinical follow-ups.

Compensation

You may be compensated for some travel expenses.

For more information, contact Jennifer Hamill at jennifer.hamill@duke.edu or 919-681-4680.