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Clinical Trials

Duke Heart Center

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A randomized, double-blind, placebo controlled study to assess the efficacy of LCQ908 on cardiovascular risk
This study is a proof of concept to determine if an investigational drug called LCQ908 can reduce triglyceride levels and lessen cardiovascular risk in people with cardiovascular disease. (REF# 35097)

Renal Denervation in Patients with Uncontrolled Hypertension -- SYMPLICITY HTN-3
Patients with uncontrolled hypertension are needed for a research study. (REF# 33607)

Studies of a Targeted Risk Reduction Intervention Through Defined Exercise in Pre-Diabetics: STRRIDE-PD
This study seeks participants between 45 and 75 years of age to evaluate the effects of different amounts and intensities of aerobic exercise. (REF# 12628)

COPE-HF: Coping Skills and Heart Failure
The COPE-HF study will evaluate if a 16-week telephone intervention focused on helping patients cope with their heart condition can improve quality of life and reduce the need for hospitalizations. (REF# 9707)

Everest II
This study seeks adults with mitral regurgitation (MR) who are seeking treatment for their condition. (REF# 11826)

IMPACT Study
This study seeks adults who are candidates for implantation of, or already implanted with, a BIOTRONIK Lumax HF-T or DR-T device. (REF# 19400)

CABANA Trial
This study seeks adult participants who have been diagnosed with an abnormal heart rhythm called atrial fibrillation (AF). (REF# 18744)

Attain StarFix Model 4195 Left Ventricular Lead Extraction
This study seeks adult participants who require a left ventricular (LV) lead removal (REF# 16665)

Lifestyle, Cardiovascular Disease Risk, and Cognitive Impairment
Adults older than age 55 are needed for a study examining how exercise and diet improve cognitive function. (REF# 31464)

Medtronic CoreValve U.S. Pivotal Trial
Researchers are seeking patients with severe degenerative aortic valve disease to participate in this study. (REF# 26293)

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URL: http://www.dukehealth.org/clinicaltrials/clinicaltrial_list?subject=Duke%20Heart%20Center