Clinical Trials

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ACT-293987 in Patients with Pulmonary Arterial Hypertension
This is a multicenter double-blind placebo-controlled phase 3 study to demonstrate the efficacy and safety of ACT-293987 in patients with pulmonary arterial hypertension. (REF# 28861)

The REVEAL Registry
Patients with pulmonary arterial hypertension are invited to be part of our multicenter, observational, US-based study of clinical course and disease management in patients with PAH. (REF# 8240)

An Evaluation of the Safety and Efficacy of the Addition of UT-15C SR to Pulmonary Arterial Hypertension Patients Currently Receiving Tyvaso
This is a multicenter open-label 24-week study to evaluate the safety and tolerability of the addition of UT-15C SR to pulmonary arterial hypertension patients currently receiving Tyvaso. (REF# 30717)

Airway Remodeling in Asthma: Modulation by IL-13
Researchers seek adult non-smokers with asthma to participate in this study. (REF# 10331)

Surfactant Protein A Regulation of Innate Immunity in Asthma
Researchers seek adult non-smokers with asthma for participation in this study. (REF# 18811)

Vitamin D Add-On Therapy Enhances Corticosteriod Responsiveness in Asthma (VIDA)
Researchers seek adults with asthma and low vitamin D levels for participation in this study. (REF# 27628)

Small Airways in Asthmatics
Duke Asthma and Airway Center is conducting a study to determine if there is a difference between the small airway in elderly people with asthma compared to younger adults with and without asthma. (REF# 31283)

Non-smokers Needed
Non-smokers are needed for several asthma research studies. (REF# 6265)

Metabolomic and Inflammatory Profiling in Patients with Chronic Obstructive Pulmonary Disease (COPD)
The purpose of this study is to look at how cells outside the lungs behave in patients with COPD (chronic bronchitis or emphysema) compared with healthy people, to determine what specific products these cells produce, and how they are affected by treatment. (REF# 3560)

Long Term Oxygen Treatment Trial (LOTT)
The purpose of this trial is to examine whether oxygen therapy prolongs and improves the quality of life in those patients who have moderately reduced oxygen levels or those who use oxygen with exercise or sleep. (REF# 13060)

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