Clinical Trials

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Awareness Study
Researchers are seeking healthy volunteers for participation in a study aimed at reducing the risk of heart disease and type 2 diabetes in at-risk individuals. (REF# 16540)

Smoking Asthmatics Research Study
Asthma patients who also smoke are needed to take part in a research study at the Duke Clinical Research Unit. The study will examine whether questionnaires used to evaluate asthma symptoms in non-smokers can also be applied to people with asthma who smoke. Participation will require 2 clinic visits that are approximately 6 weeks apart. (REF# 41549)

A randomized, double-blind, placebo controlled study to assess the efficacy of LCQ908 on cardiovascular risk
This study is a proof of concept to determine if an investigational drug called LCQ908 can reduce triglyceride levels and lessen cardiovascular risk in people with cardiovascular disease. (REF# 35097)

A Phase 3 Randomized, Double-Blind, Multicenter, Placebo-Controlled, Combination Study to Evaluate the Efficacy and Safety of Lesinurad and Allopurinol Compared to Allopurinol Alone in Subjects with Gout who have had an Inadequate Hypouricemic Response to Standard of Care Allopurinol
To determine the efficacy of an investigational new medication, lesinurad, when used in combination with allopurinol compared to using allopurinol alone.
(REF# 37670)

Effect of Positive Airway Pressure on Reducing Airway Reactivity in Patients with Asthma
Asthma patients who do not smoke and have been using medication for at least a year are needed to take part in a research study at the Duke Clinical Research Unit. (REF# 34572)

Branched-chain Amino Acid Metabolism in Pre-Diabetes: BCAAM-PD
The purpose of this study is to investigate how the Branched-chain Amino Acids contribute to insulin resistance in overweight and obese individuals and their source in the plasma. (REF# 00034434)

Diabetes Food and Mood Study
Patients with type 1 diabetes are needed for a study examining the relationship diabetics have with eating and weight. (REF# 31840)

ENHANCED
We are recruiting subjects for a clinical trial of exercise and stress management called ENHANCED. (REF# 15896)

Studies of a Targeted Risk Reduction Intervention Through Defined Exercise in Pre-Diabetics: STRRIDE-PD
This study seeks participants between 45 and 75 years of age to evaluate the effects of different amounts and intensities of aerobic exercise. (REF# 12628)

Lifestyle, Cardiovascular Disease Risk, and Cognitive Impairment
Adults older than age 55 are needed for a study examining how exercise and diet improve cognitive function. (REF# 31464)