Clinical Trials

The clinical trials below are available in the specialty you selected. Choose a different specialty.

Smoking Asthmatics Research Study
Asthma patients who also smoke are needed to take part in a research study at the Duke Clinical Research Unit. The study will examine whether questionnaires used to evaluate asthma symptoms in non-smokers can also be applied to people with asthma who smoke. Participation will require 2 clinic visits that are approximately 6 weeks apart. (REF# 41549)

A randomized, double-blind, placebo controlled study to assess the efficacy of LCQ908 on cardiovascular risk
This study is a proof of concept to determine if an investigational drug called LCQ908 can reduce triglyceride levels and lessen cardiovascular risk in people with cardiovascular disease. (REF# 35097)

Dietary Nitrate to Augment Exercise Training Benefits in DM+PAD
We are seeking approximately 28 people (ages 40-80) with peripheral arterial disease and type II diabetes. This study is based at the Non-Invasive Vascular Laboratory at the Duke Center for Living campus. (REF# Pro00039608)

A Phase 3 Randomized, Double-Blind, Multicenter, Placebo-Controlled, Combination Study to Evaluate the Efficacy and Safety of Lesinurad and Allopurinol Compared to Allopurinol Alone in Subjects with Gout who have had an Inadequate Hypouricemic Response to Standard of Care Allopurinol
To determine the efficacy of an investigational new medication, lesinurad, when used in combination with allopurinol compared to using allopurinol alone.
(REF# 37670)

Effect of Positive Airway Pressure on Reducing Airway Reactivity in Patients with Asthma
Asthma patients who do not smoke and have been using medication for at least a year are needed to take part in a research study at the Duke Clinical Research Unit. (REF# 34572)

Safety and Efficacy of a Lysophosphatidic Acid Receptor Antagonist in Idiopathic Pulmonary Fibrosis
To evaluate the safety and tolerability of treatment with an investigational drug versus a placebo in volunteers with a diagnosis of IPF. (REF# 41242)

A randomized, double-blind, 12- week, parallel group, placebo-controlled study of the efficacy and safety of RO4917523 in patients with Fragile X Syndrome
FIXME (REF# Pro00039844)

Long-Acting Beta Agonist Step Down Study (LASST)
Males and females, age 12 years and older are needed to participate in a research study to evaluate the optimal treatment strategy for reducing therapy in people with asthma. (REF# Pro00034544)

Renal Denervation in Patients with Uncontrolled Hypertension -- SYMPLICITY HTN-3
Patients with uncontrolled hypertension are needed for a research study. (REF# 33607)

Diabetes Food and Mood Study
Patients with type 1 diabetes are needed for a study examining the relationship diabetics have with eating and weight. (REF# 31840)