The goal of the APS study is to determine the genetic link in families with one or more affected individuals.

Eligibility includes the APS affected individual having at least one aPL positive titer and a clinical symptom such as a thrombosis event or pregnancy morbidity.

Eligibility for relatives includes family members with or without APS or other autoimmune disorders including (but not limited to) rheumatoid arthritis, SLE, multiple sclerosis, autoimmune thyroid disease, type I diabetes mellitus, psoriasis, inflammatory bowel disease, scleroderma, and myasthenia gravis.

There are up to two blood draws at least six weeks apart.

There is no compensation for participation.

For more information, contact Sharon Hall at 919-681-9565 or sharon.hall@duke.edu.