Clinical Trials
Cancer clinical trials help answer important questions about medical care in an effort to develop new and improved ways to treat all patients with cancer and those who will develop cancer in the future.
Find current clinical trials offered by Duke Cancer Institute:
Research Overview
Researchers at the Duke Cancer Institute are continually studying sarcomas and new therapies aimed at treating them. Some highlights from the Duke Sarcoma Site-Based Research Program:
- Researchers are studying sarcomas in children, adolescents, and young adults. Areas of interest include investigation of new agents for rhabdomyosarcoma patients who have the lowest chance of long-term survival.
- David Kirsch, MD, PhD, has developed an animal model of soft tissue sarcoma that is being used in a variety of projects to identify improved treatments for patients.
- Members of the Duke sarcoma team, along with engineers from the Massachusetts Institute of Technology are developing a device to image tumor cells intraoperatively to improve surgical treatment.
- Surgical oncologist Douglas Tyler, MD, and colleagues are studying methods for improving regional therapies for sarcomas. They have developed animal models that mimic the human clinical situation of advanced extremity sarcoma, and are testing new drugs that block cancer cells’ resistance to anti-cancer treatment.
- Duke is using specialized image-guided radiation therapy, which allows radiation to be focused on the tumor. This may cause less damage to normal tissue. Duke enrolled patients in a multi-institutional trial studying the side effects and how well image-guided radiation therapy works in treating patients with primary soft tissue sarcoma of the shoulder, arm, hip, or leg.
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