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Clinical Trials

Cancer clinical trials help answer important questions about medical care in an effort to develop new and improved ways to treat all patients with cancer and those who will develop cancer in the future.

Find current clinical trials offered by Duke Cancer Institute:

  • Pediatric brain tumors
  • Pediatric leukemias and myeloproliferative syndromes
  • Pediatric lymphomas
  • Pediatric neuroblastomas, embryonal, and germ cell tumors
  • Pediatric phase I and II clinical trials
  • Pediatric sarcomas
  • Wilms' tumor
  • All cancer clinical trials

Research Overview

The pediatric cancer program is part of the Duke Cancer Institute. One of only 40 centers in the country designated by the National Cancer Institute (NCI) as a “comprehensive cancer center,” Duke combines cutting-edge research with compassionate care.

Each new discovery is brought rapidly into the clinic where doctors work to provide patients with the most promising therapies available.

Within the Duke Cancer Institute there is ongoing research into many different aspects of childhood cancer and its treatment, including:

  • The use of unrelated umbilical cord blood to treat resistant cancers as well as immune deficiencies and rare metabolic diseases for which there is no other cure
  • Lifestyle change interventions to improve health in cancer survivors
  • Fertility preservation in cancer patients
  • Developing mouse models of acute myeloid leukemia (AML) to investigate novel mechanisms by which AML develops in infants
  • Investigating pathways that may lead to novel approaches for the treatment of brainstem gliomas
  • Psychological issues in children and families dealing with chronic illness
  • Cancer genetics and genomics
  • Targeting pathways that lead to the formation of pediatric muscle tumors (rhabdomyosarcomas) in an effort to develop new treatment interventions
  • Clinical trials studying novel treatments for pediatric cancers including leukemias, lymphoma, neuroblastoma, embryonal tumors, and bone and muscle tumors
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About This Page

Updated: Aug. 22, 2011
Published: Aug. 22, 2011
URL: http://www.dukehealth.org/cancer/patient-care-services/pediatric-cancer/about/clinical-trials/index