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Home > Patient Care Services > Pediatric Cancer > About > Care Guides > Chemotherapy for Pediatric Cancers
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Published: Aug. 26, 2011
Updated: Aug. 26, 2011

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Chemotherapy involves administering drugs that kill cancer cells.

Systemic chemotherapy is administered to the whole body via an oral medication or an injection. Regional chemotherapy is administered to just one part of the body such as the spinal cord, an organ such as the liver, or a part of the body such as the abdomen.

Chemotherapy is frequently an outpatient procedure.

Chemotherapy with Stem Cell Treatment

In this treatment, high doses of systemic chemotherapy are administered, which destroys the cancer cells, but as a side effect, other normal cells in the bone marrow are also killed.

The patient then receives an infusion of stem cells, which will develop into new, healthy bone marrow cells. These stem cells may be the patient's own (autologous stem cell rescue -- harvested from the patient before receiving high dose chemotherapy), or they may be from a related or unrelated donor (allogenic stem cell transplant).

Chemotherapy with stem cell treatment may be used to treat some types of brain tumors, leukemias, lymphomas, and recurrent Ewing sarcoma.

Side Effects of Chemotherapy

Chemotherapy is effective at killing cancer cells, but it can kill normal cells too, resulting in side effects. Your child's doctor will adjust your regimen to reduce side effects as much as possible.

Side effects of chemotherapy can include:

  • Nausea
  • Vomiting
  • Hair loss
  • Sores inside the mouth
  • Diarrhea
  • Lack of appetite
  • Fatigue
  • Increased chance of infection
  • Tendency to bruise easily

Learn more about pediatric cancer:

  • Radiation Therapy for Pediatric Cancer
  • Pediatric Cancer Risk Factors
  • Late Effects of Pediatric Cancer Treatment
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About This Page

Updated: Aug. 26, 2011
Published: Aug. 26, 2011
URL: http://www.dukehealth.org/cancer/patient-care-services/pediatric-cancer/about/care_guides/chemotherapy-for-pediatric-cancers