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Home > Patient Care Services > Leukemias, Lymphomas, and Myelomas > About > Care Guides > Stages of Lymphoma
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Published: Sept. 2, 2011
Updated: Sept. 2, 2011

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Some types of lymphoma are not divided into stages but are classified according to their treatment status. Others are divided into stages 0 through IV, according to how advanced they are.

Hodgkin Lymphoma

Hodgkin lymphoma is classified into four groups:

  • “A” means the patient has so symptoms
  • “B” which means the patient has symptoms such as fever, weight loss, and night sweats
  • “E” or “extranodal” means the cancer is found in an area outside the lymph nodes
  • “S” or “spleen” means the cancer is found in the spleen.

Hodgkin lymphoma is further divided into the following stages:

  • Stage I: Cancer is confined to lymph nodes in one group, or it is found outside the lymph nodes but in only one organ
  • Stage II: The cancer is in two or more different lymph node groups, or it is in one organ as well as nearby lymph nodes. But it is still limited to either the area above or the area below the diaphragm (the muscle that separates the chest from the abdomen).
  • Stage III:  The cancer is found in lymph nodes both above and below the diaphragm. The cancer may also be in one organ or tissue near the lymph nodes, or the spleen
  • Stage IV: Cancer is in several parts of one or more organs or tissues such as the bones, the liver, or the lungs.

Non-Hodgkin Lymphoma

Non-Hodgkin lymphoma is divided into the following stages:

  • Stage I: Cancer is found in one group of lymph nodes or in one area outside the lymph nodes
  • Stage II: Cancer is found in one area outside the lymph nodes and in nearby lymph nodes
  • Stage III: Cancer is found below the diaphragm or in two or more areas noted in stage I, or it may have started in the stomach or intestines and may be able to be removed by surgery. It may or may not have spread to nearby lymph nodes.
  • Stage IV: Cancer is found in the brain, bone marrow, or cerebrospinal fluid. It may also be in other parts of the body.

Further staging may include references to “E” or “extranodal,” which means the cancer is found in an area outside the lymph nodes, or as “S” or “spleen,” which means the cancer is found in the spleen.

Learn more about leukemias and lymphomas:

  • Types of Lymphoma
  • Lymphoma Risk Factors
  • Treatment Options for Leukemias and Lymphomas
  • Symptoms of Leukemias and Lymphomas
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About This Page

Updated: Sept. 2, 2011
Published: Sept. 2, 2011
URL: http://www.dukehealth.org/cancer/patient-care-services/leukemias-and-lymphomas/about/care_guides/stages-of-lymphoma