Clinical Trials
Cancer clinical trials help answer important questions about medical care in an effort to develop new and improved ways to treat all patients with cancer and those who will develop cancer in the future.
Find current clinical trials offered by Duke Cancer Institute:
Research Overview
The Preston Robert Tisch Brain Tumor Center at Duke boasts:
- One of the largest libraries of tumor cell lines in the world, allowing researchers to study the complex mechanisms of brain tumors and devise better ways of battling them.
- Recognition by the National Institutes of Health as a leader in the research and treatment of brain tumors -- including designation as one of the nation’s only Specialized Research Centers on Primary Tumors of the Central Nervous System from the National Institute of Neurological Disorders and Stroke.
- More active clinical trials than any other known treatment center.
We offer many experimental treatments -- most developed in our own laboratories -- to subdue aggressive brain tumors, overcome drug-resistant tumors, and manipulate the genes and proteins that fuel a tumor’s growth. Several brain tumor treatment vaccines are available.
Duke brain tumor researchers have also combined the cancer-killing properties of varying viruses or toxins with a harmless genetic coding element from the common cold to create an anti-cancer agent that was very effective in killing brain cancer (as well as breast cancer and colon cancer) in the laboratory. Doctors expect to test these new treatments in humans in the next few years.
Chemotherapy drugs of great promise are being developed to treat brain tumors. Our current research focuses on the mechanisms by which tumors become resistant to chemotherapy and ways to reverse this resistance. Several clinical trials are in progress.
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