Duke Cancer Institute
Patient Care
Research Programs
Explore all health services at muto-logo.gif

Welcome to DukeHealth.org.
Skip over navigation
  • Home
  • Patient Care Services
  • Support Services
  • Physicians
  • Locations
  • Clinical Trials
  • Patient and Visitor Guide
  • Health Library
  • About Us

Quick Links

  • Appointments
  • Referring Physicians
  • Giving to DCI
Home > Patient Care Services > Brain Tumors > About > Care Guides > Brain Tumor Risk Factors
Jumbo Large Regular Text:
Print
Brain Tumors
About
Care Guides Support Services Clinical Trials News Events Patient Stories Appointments
Tests and Treatments
Medical Therapy Radiation Therapy Surgery
Physicians
Locations

Brain Tumor Risk Factors

Make an appointment

888-ASK-DUKE
(888-275-3853)

Cancer Center Calendar

About This Article

Article Details

Published: Sept. 2, 2011
Updated: Sept. 2, 2011

Share

While much is unknown about the causes of brain tumors, certain inherited genetic syndromes may increase risk. Keep in mind that not everyone with these risk factors will get a brain tumor, and many people with brain tumors have none of these risk factors.

Radiation therapy. Having had radiation to the head or scalp to treat earlier cancers can increase risk of a brain tumor. This most commonly occurs in people who had treatment of childhood cancer, such as leukemia. Radiation exposure accounts for less than 1 percent of brain tumors.

Genetic syndromes. Changes in particular genes cause people with certain inherited syndromes to develop cancers in the brain and central nervous system as well as other areas of the body. These syndromes include:

  • Neurofibromatosis type 1 or 2
  • von Hippel-Lindau disease
  • Tuberous sclerosis
  • Li-Fraumeni syndrome
  • Turcot syndrome type 1 and type 2
  • Klinefelter syndrome
  • Nevoid basal cell carcinoma syndrome

Only about 5 percent of brain tumors are associated with inherited genetic syndromes.

Immune system disorders. Inherited immune-system dysfunction or acquired syndromes such as HIV or AIDS can increase the risk of developing lymphomas of the brain or spinal cord.

Learn more about brain tumors:

  • Brain Tumor Symptoms
  • Types of Brain Tumors
  • Brain Tumor Grades
Facebook
Twitter
YouTube
Contact Us | Careers | Make a Gift | Site Map
Duke Medicine | Duke School of Medicine | Duke University
Toll-Free: 888-ASK-DUKE (888-275-3853)
Copyright © 2004-2013 Duke University Health System

About This Page

Updated: Sept. 2, 2011
Published: Sept. 2, 2011
URL: http://www.dukehealth.org/cancer/patient-care-services/brain-tumors/about/care_guides/brain-tumor-risk-factors