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Skin Cancer
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Medical and Radiation Therapies

Duke medical and radiation oncologists are at the forefront of efforts to develop and deliver innovative new treatments for skin cancers.

Working closely with our surgeons, these specialists provide conventional and experimental treatments before and after surgery.

Duke medical oncologists offer a full range of biologic therapies, including immune-based and targeted treatments that can only be administered by highly experienced doctors and nurses.

Innovative Therapies

Duke is one of a limited number of centers offering high-dose Interleukin-2 (IL-2) to melanoma patients.

In addition, we are one of only a few centers combining experimental drugs with high-dose IL-2 in clinical trials to try to improve its effectiveness.

To more effectively treat melanomas that invade the brain, Duke is conducting clinical studies combining the widely used anti-cancer drug temozolomide with arsenic trioxide, which encourages cancer cells to self-destruct.

Such therapies are used for patients with regionally advanced inoperable melanoma or for patients with stage IV melanoma that has spread to other organs.

Additionally, Duke is one of a limited number of cancer centers in the Southeast that has the expertise to offer patients treatment with high-dose interferon alpha, a therapy used to prevent recurrences in patients with stage II or stage III melanoma.

Duke also conducts clinical trials testing new ways to use interferon-based therapies, as well as vaccine therapies, to prevent recurrences in patients with stage II and stage III melanoma.

Regional therapies are used for some patients who have surgically incurable cancers confined to one limb.

All skin cancer and melanoma patients seen at Duke benefit from regular surveillance appointments with a Duke dermatologist to check for new lesions.

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